Type
Mesotherapy
Duration
45 min
What's included
4 deliverables in this treatment
- EMLA numbing cream applied 20–30 minutes before treatment
- REJURAN polynucleotide microinjections by physician
- Post-treatment care instructions
- Recommended session schedule for optimal results
REJURAN is a bio-stimulatory injectable made from polynucleotides (PN) derived from salmon gonad DNA. At RVmedCentrum it is used for facial skin regeneration, under-eye rejuvenation, scar improvement, and hand treatment. The polynucleotide chains stimulate fibroblast activity, increasing collagen and elastin production while reducing inflammation and restoring the skin's barrier function. Three formulations are available: Healer for face and body, I for the delicate eye area, and S for acne scars and other scarring.
About this treatment
REJURAN is a polynucleotide (PN) skin bio-stimulator developed in South Korea and backed by clinical studies showing improvements in skin elasticity, hydration, and wound healing. The active ingredient is fragments of salmon DNA — a source chosen because salmon polynucleotides have a particularly high affinity for human skin cells and stimulate fibroblast regeneration without triggering an immune response.
Unlike hyaluronic acid fillers, which primarily add volume, REJURAN works at the cellular level to improve the skin's intrinsic quality: increasing collagen and elastin synthesis, reducing chronic inflammation in aged or damaged skin, and repairing the skin barrier. The result is a gradual, natural improvement in skin texture, radiance, and resilience rather than an immediate volumising effect.
RVmedCentrum offers three REJURAN formulations: - REJURAN Healer (6,900 Kč): broad bio-stimulation for the face, neck, and décolletage. Most commonly used for overall anti-aging and skin quality improvement. - REJURAN I (6,000 Kč): formulated specifically for the delicate periorbital area (under the eyes) and the backs of the hands, where the skin is too thin for standard filler approaches. - REJURAN S (6,000 Kč): a thicker formulation for intradermal use…
Good to know
- Active ingredient
- Polynucleotides (PN) from salmon gonad DNA
- Effect
- Collagen stimulation + inflammation reduction + barrier repair
- Formulations
- Healer / I (eye/hands) / S (scars)
- Series
- 3 sessions at 2–4 week intervals
- Downtime
- Redness/bumps 24–48h; avoid makeup 48h
Who is this for?
Adults from 25 wanting genuine skin quality improvement rather than volume, particularly those with dull, dehydrated, or aging skin, periorbital concerns, or acne scarring
Preparation required
Arrive 30 minutes early for numbing cream application. Avoid alcohol and blood-thinning supplements for 24 hours prior. Do not apply makeup or sunscreen on the day.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
147 clinic reviews
From independent platforms
Clinical team
RVmedCentrum is led by MUDr. Radan Vidura, Ph.D., an ENT and head-and-neck surgeon with over 25 years of rhinoplasty experience. Aesthetic dermatology is provided by MUDr. Blanka Žuffová-Kunčová, MUDr. Dita Vitovjáková, and MUDr. Viktor Palla (dermatovenereology), with MUDr. Andrea Jelínková specialising in aesthetic dermatology and MUDr. Chantal Kožaková in general surgery and non-invasive facial contouring. Eyelid…
Languages: Czech
What clients say
"{"author":"Van33","date":"2025-10-01","procedure":"Rhinoplasty","text":"Dr Vidura explained everything clearly, the procedure went smoothly, and there was no pain whatsoever. Minimal bruising and a result I am extremely happy with."}"
"{"author":"lenulinka","date":"2025-07-01","procedure":"Bullhorn Lip Lift","text":"I underwent the Bullhorn Lip Lift with Dr Vidura and I am very satisfied. Professional team and a natural result."}"
Treatment highlights
- EMLA numbing cream applied 20–30 minutes before treatment
- REJURAN polynucleotide microinjections by physician
+2 more items in What's included
REJURAN Healer (face, neck, décolletage): 6,900 Kč per session. REJURAN I (eye area, hands): 6,000 Kč. REJURAN S (scars, acne scars): 6,000 Kč. Recommended series of 3 sessions at 2–4 week intervals.