IVF with Egg Donation Prague

IVF with egg donation at Royal Medical Prague uses anonymous Czech donors matched by phenotype (hair colour, eye colour, blood group) and aged 18–35, fully screened for genetic disease and STDs. The programme reports a 65% clinical pregnancy rate per transfer with donated eggs — substantially higher than IVF with a patient's own eggs for women over 40. No waiting lists apply, and treatment is available to women up to age 49. Royal Medical coordinates this with Dr. Jan Lacheta's fertility team, who have facilitated more than 10,000 successful IVF births. Genetic embryo screening (PGD/PGS) is available for optimal embryo selection. From €5,400 all-inclusive, this is a fraction of UK or US egg donation IVF pricing.

IVF with oocyte (egg) donation through Royal Medical Prague is coordinated with a partner fertility clinic led by Dr. Jan Lacheta, a reproductive endocrinologist credited with facilitating more than 10,000 successful births through assisted reproduction in his career. The programme is open to women up to age 48 years 364 days — consistent with the Czech regulatory framework — and is primarily sought by women whose own egg quality or ovarian reserve is insufficient for successful IVF with own eggs (a common situation from age 38–40 onward), women who have experienced repeated IVF failure with own eggs, premature ovarian insufficiency (early menopause), genetic diseases transmissible through maternal eggs, or women who wish to avoid passing on known hereditary conditions. Donor selection in the Czech Republic follows an anonymous model — donors are not identified to the recipient, and the recipient's identifying information is not provided to the donor. Matching is done by the clinic's team based on phenotypic criteria: hair colour, eye colour, blood group, and general physical build. Donors are aged 18–35, have completed their own family or are young nulliparous women who undergo thorough medical screening before acceptance. This screening covers karyotyping (chromosomal analysis), genetic carrier testing for common hereditary disorders, infectious disease screening (HIV, Hepatitis B and C, syphilis, chlamydia), and a psychological evaluation. Fertilisation is performed using the partner's sperm (or donor sperm if required) by one of several laboratory methods: standard IVF (co-incubation of eggs and sperm), ICSI (intracytoplasmic sperm injection — a single sperm injected directly into each egg, used when sperm quality is suboptimal), PICSI (physiological ICSI, which selects sperm by their ability to bind hyaluronic acid — a selection mechanism that filters out DNA-damaged sperm), or MACS (magnetic-activated cell sorting, which removes apoptotic sperm from the sample before fertilisation). The choice of fertilisation method is made by the embryologist based on the couple's sperm analysis. Optional preimplantation genetic testing (PGD/PGS) allows embryos to be biopsied and screened for chromosomal aneuploidies (PGS) or specific genetic diseases (PGD) before transfer, selecting only euploid (chromosomally normal) embryos. This is associated with higher per-transfer success rates and reduced miscarriage risk, particularly in older recipients. The clinical pregnancy rate of 65% per transfer with donated eggs is substantially higher than the 10–15% per transfer typically achieved with own eggs in women over 42, reflecting both the quality of younger donor eggs and the selective donor-screening process. Royal Medical reports no waiting times — a significant advantage over many UK NHS and private IVF programmes, where egg donation cycles can involve waiting lists of 6–18 months. The first visit to Prague (typically 7–10 days) covers the recipient's gynaecological and ultrasound examination, endometrial preparation (hormone treatment to synchronise the uterine lining with the donated embryo), embryo transfer, and the recipient's initial follow-up. A pregnancy test is performed 17–20 days after transfer. The all-inclusive fee of approximately €5,400 covers the recipient's clinical protocol; hormonal stimulation medications are a separate cost handled by the patient's home country prescriber or the Prague clinic.