NAD+ IV Drip Therapy

NAD+ (nicotinamide adenine dinucleotide) IV infusions at Restore Denver deliver this foundational coenzyme directly into the bloodstream to support cellular energy metabolism, DNA repair, and longevity-associated signalling pathways. Available in 500 mg and 750 mg doses as IV drips, and as faster intramuscular shots. Niagen (nicotinamide riboside, NR) IV and IM options are also available as NAD+ precursors.

Restore Hyper Wellness South Broadway offers NAD+ IV therapy — a premium longevity-focused intravenous infusion delivering nicotinamide adenine dinucleotide directly into the bloodstream. NAD+ is a coenzyme found in every cell of the body and is central to numerous metabolic processes: it functions as an electron carrier in the mitochondrial oxidative phosphorylation chain (Complexes I and III), enabling the conversion of nutrients from food into ATP, the cell's primary energy currency. Beyond energy metabolism, NAD+ is the required substrate for sirtuins (SIRT1–7), a family of deacylase enzymes involved in chromatin remodelling, DNA damage repair, inflammatory signalling, and mitochondrial biogenesis — pathways strongly implicated in the biology of aging at the cellular level. NAD+ is also consumed by PARP enzymes (poly-ADP-ribose polymerases) during DNA strand break repair, depleting cellular NAD+ pools rapidly during periods of oxidative stress or genotoxic exposure. Systemic NAD+ levels decline progressively with age and with disease states, and IV NAD+ administration is used by practitioners as a direct repletion strategy bypassing the salvage and biosynthetic pathways. The Restore menu offers 500 mg and 750 mg NAD+ IV doses; higher doses are associated with a slower infusion rate to minimise the transient chest tightness, flushing, and nausea that NAD+ can cause when administered too rapidly. Sessions run approximately 90 minutes at the 500 mg dose and longer for 750 mg. Niagen (nicotinamide riboside, NR) IV and IM options are offered as alternative NAD+ precursors for clients who prefer a faster administration or different price point. Intramuscular NAD+ shots provide a briefer, lower-dose alternative for ongoing maintenance between IV sessions. All NAD+ and Niagen sessions are RN-administered.