NAD+ IV Therapy

An intravenous infusion of nicotinamide adenine dinucleotide (NAD+), a coenzyme central to cellular energy metabolism, DNA repair, and sirtuin activation. NAD+ levels decline naturally with age, and IV supplementation delivers the molecule directly into the bloodstream at concentrations that oral NMN or NR precursors cannot match.

The NAD+ IV Therapy at RE:BERRY Clinic delivers nicotinamide adenine dinucleotide directly into the bloodstream through a controlled intravenous infusion. NAD+ is a coenzyme found in every living cell, where it plays essential roles in redox reactions that drive mitochondrial energy production (as a carrier of electrons in the electron transport chain), DNA repair mechanisms (as a substrate for PARP enzymes), and epigenetic regulation (as a substrate for sirtuin deacetylases). Research has documented that NAD+ levels decline with age across multiple tissues, and this decline is associated with reduced mitochondrial function, impaired DNA repair capacity, and altered gene expression patterns. The longevity research community has identified NAD+ replenishment as one of the more promising intervention targets, which has driven interest in both oral precursors (NMN, NR) and direct IV NAD+ administration. Intravenous delivery offers a pharmacokinetic advantage over oral precursors because it bypasses the multi-step enzymatic conversion pathway that NMN and NR must traverse to become NAD+ inside cells. While the body can synthesise NAD+ from these precursors, the conversion efficiency varies between individuals and is influenced by age, liver function, and competing metabolic demands. IV NAD+ provides the finished molecule directly. The infusion is administered slowly, typically over 60 minutes, because rapid NAD+ infusion can cause temporary flushing, chest tightness, or nausea in some patients. The physician adjusts the drip rate based on patient tolerance, and vital signs are monitored throughout. Patients report varied subjective experiences — some describe increased mental clarity and energy within hours, while others notice effects gradually over subsequent days. RE:BERRY's standard NAD+ session represents the entry-level dose. The clinic also offers enhanced and premium-dose options for patients who have tolerated the standard infusion previously and want to increase the amount per session. A physician consultation before the first NAD+ session assesses suitability, covering cardiovascular history, current medications, and prior IV therapy experience. The clinic's year-round availability and Myeongdong location make NAD+ therapy accessible to both Seoul residents and visitors, with WhatsApp booking available for advance scheduling and walk-ins accepted when infusion chairs are open.