Type
Blood Testing
Biomarkers
8
Duration
15 min
A five-biomarker thyroid panel measuring TSH, free T3, free T4, anti-TPO, and anti-TG antibodies. Goes beyond the standard GP thyroid screen by including both active thyroid hormones and autoimmune markers. Results in 24 hours.
Most GP thyroid checks measure only TSH — and while this is a useful screening marker, it tells you nothing about the active thyroid hormones that tissues actually respond to, nor whether an autoimmune process is attacking the thyroid gland. This panel addresses both gaps by including the full functional and autoimmune picture in five markers. Free T3 and free T4 are the biologically active thyroid hormones. T4 is the primary output of the thyroid gland and must be converted to T3 (the more potent form) in peripheral tissues. Some individuals have normal TSH but impaired T4-to-T3 conversion, which standard TSH-only screening would miss entirely. The relationship between TSH and the free hormones provides substantially more diagnostic information than any single marker. Anti-TPO and anti-TG antibodies detect Hashimoto's thyroiditis and other autoimmune thyroid conditions, which are among the most common autoimmune disorders and can cause symptoms years before TSH moves outside the reference range. Early identification of thyroid autoimmunity allows for monitoring and timely intervention. At 60 pounds, this panel is remarkably cost-effective for the breadth it provides and is particularly valuable for individuals with a family history of thyroid disease, unexplained fatigue, weight changes, or mood disturbances.
Key Details
- Biomarkers
- 5
- Includes
- Autoimmune markers
- Results
- 24 hours
- Accreditation
- UKAS ISO 15189
Who Is This For?
Thyroid health screening, family history of thyroid disease, unexplained fatigue, weight changes, mood disturbances, autoimmune thyroid detection
What's Included
Panel Categories
Biomarkers Tested
8The active form of thyroid hormone responsible for regulating metabolism, energy, and body temperature. Free T3 is converted from T4 in tissues and is three to four times more potent than T4.
The unbound, active form of the main thyroid hormone T4. Free T4 directly reflects thyroid gland output and is used alongside TSH to diagnose and monitor thyroid disorders.
Free triiodothyronine; high levels indicate hyperthyroidism, low levels hypothyroidism.
Free thyroxine; high levels indicate hyperthyroidism, low levels hypothyroidism.
A group of proteins in blood including antibodies (immunoglobulins), transport proteins, and enzymes. Elevated globulin can indicate chronic infection, inflammation, or blood cancers. Calculated by subtracting albumin from total protein.
An inactive form of T3 produced when the body converts T4. Elevated reverse T3 can occur during illness, stress, or caloric restriction and may indicate impaired thyroid hormone activation despite normal TSH levels.
Antibodies against thyroid peroxidase, an enzyme essential for thyroid hormone production. Positive TPO antibodies indicate autoimmune thyroid disease, most commonly Hashimoto's thyroiditis, even before symptoms or TSH changes appear.
The primary screening test for thyroid function. TSH is produced by the pituitary gland to regulate thyroid hormone production. High TSH indicates an underactive thyroid (hypothyroidism), while low TSH suggests an overactive thyroid (hyperthyroidism).
- Category
- Diagnostic
- Duration
- 15 min