NAD+ Infusion Therapy

High-dose NAD+ intravenous infusions to restore cellular energy metabolism, support DNA repair, activate sirtuins linked to longevity, and counteract the age-related decline in NAD+ levels throughout the body.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme central to virtually every cell's energy production and DNA repair mechanisms. By the age of 40, NAD+ levels in the body have declined by approximately 50% from peak youthful levels, and this decline accelerates with age, chronic illness, alcohol use, poor sleep, and metabolic dysfunction. Restoring NAD+ through intravenous infusion is one of the most scientifically substantiated longevity interventions available today, and R17's positioning as a precision longevity centre makes it a natural fit for this therapy. NAD+ IV infusions deliver nicotinamide adenine dinucleotide directly into the bloodstream, bypassing the low bioavailability of oral precursors like NMN and NR. At therapeutic doses, IV NAD+ rapidly elevates intracellular NAD+ concentrations, activating key longevity pathways including sirtuin enzymes (SIRT1-7), which govern DNA repair, mitochondrial biogenesis, inflammation regulation, and metabolic efficiency. PARP enzymes responsible for genome surveillance and repair are also NAD+-dependent, meaning adequate levels are critical for reducing accumulated DNA damage. Clients typically report increased mental clarity, elevated energy levels, improved mood, and enhanced physical performance in the days following infusion. For individuals with chronic fatigue, neurological symptoms, or those recovering from illness or addiction, therapeutic doses are often higher and administered over multiple consecutive sessions. For longevity and performance optimisation in otherwise healthy individuals, maintenance protocols might involve monthly infusions alongside lifestyle and dietary NAD+ precursor support. At R17, NAD+ therapy is prescribed and monitored by physicians, with dosing adjusted based on individual tolerance — infusion rate is carefully controlled as higher doses can cause transient side effects including warmth, chest tightness, and nausea if administered too rapidly. Sessions are conducted in a comfortable clinic environment with full nursing supervision throughout the 3-4 hour infusion window.