Quest Diagnostics Type 1 Diabetes Autoantibody Screening Test
Type
Blood Testing
Biomarkers
6
Duration
30 min
Results
24 hours
Comprehensive blood test to screen for autoantibodies indicating increased risk of developing type 1 diabetes.
This test screens for four autoantibodies linked to a higher risk of developing type 1 diabetes (T1D). Many people with T1D don't have a family history, but those with a relative diagnosed are at significantly higher risk. Early detection allows for potential delay of disease onset with new treatments, reduced symptom severity, and fewer long-term complications. The test measures insulin autoantibody (IAA), tyrosine phosphatase IA2, glutamic acid decarboxylase (GAD65), and zinc transporter 8 (ZnT8) levels.
Key Details
- Biomarkers
- 2–4 metabolic markers
- Fasting Required
- Yes, 10–12 hours for fasting glucose
- Sample Type
- Blood draw
- Turnaround
- Same day to 24 hours
- Common Use
- Diabetes screening, insulin resistance detection
Who Is This For?
Adults over 35 as part of routine screening (diabetes affects 1 in 10 adults globally). Anyone with a family history of type 2 diabetes. People who are overweight or physically inactive. Those experiencing increased thirst, frequent urination, unexplained weight loss, or fatigue. Women with a history of gestational diabetes or polycystic ovary syndrome (PCOS).
What's Included
Preparation Required
Fasting for 10–12 hours before your appointment is recommended for accurate results (water is fine). Avoid alcohol for 24 hours and intense exercise for 12 hours before the blood draw. Morning appointments are ideal for consistent hormone and glucose readings. The blood draw typically takes 5–10 minutes.
Biomarkers Tested
6The hormone produced by the pancreas to regulate blood sugar. Elevated fasting insulin — even with normal glucose — is an early marker of insulin resistance, which precedes type 2 diabetes by years. Key biomarker in longevity medicine.
Imbalances in gut pH influence short-chain fatty acid production and their effects.
Autoantibodies to an enzyme in pancreatic beta cells; often develop first in children ages 3-5.
An essential trace mineral involved in immune function, wound healing, DNA synthesis, and testosterone production. Zinc deficiency impairs immune response, delays wound healing, and can cause hair loss and taste changes.
Blood sugar — the body's primary energy source. Fasting glucose screens for diabetes and prediabetes. Chronically elevated glucose damages blood vessels and organs. Levels fluctuate with meals, stress, and physical activity.
Reflects your average blood sugar over the past 2–3 months by measuring the percentage of hemoglobin with attached glucose. HbA1c is the gold standard for diagnosing and monitoring diabetes, unaffected by daily fluctuations.
+ $6.00 Physician Service Fee
- Category
- Diagnostic
- Sample Type
- Blood draw
- Duration
- 30 min
- Results
- 24 hours