Quest Diagnostics Perimenopause Test Panel
Type
Blood Testing
Biomarkers
10
Duration
30 min
Results
4 days
Measure hormones that impact your menstrual cycle and reproductive health as a way to kickstart an informative conversation with your healthcare provider. For women 45 years and older. If your test results are abnormal, an independent physician may be able to provide you with treatment options.
This panel measures follicle-stimulating hormone (FSH), estradiol, luteinizing hormone (LH), and thyroid stimulating hormone (TSH) levels in the blood to help determine if you’re entering or are already in the perimenopause transition phase. This panel may be helpful for women who have a history of irregular menstrual periods and a negative pregnancy test to help you and your doctor decide next steps for handling any symptoms you may be experiencing. The test provides insights into hormone levels impacting menstrual cycles and reproductive health. Results can inform conversations with healthcare providers about potential treatment options if abnormalities are detected. It's designed for women 45 and older experiencing menstrual changes or symptoms like hot flashes. This test helps determine menopausal status and guide further medical decisions.
Key Details
- Biomarkers
- 4–12 hormone markers
- Fasting Required
- Not required, but morning draw recommended
- Sample Type
- Blood draw
- Turnaround
- 2–5 business days
- Timing Note
- Morning draw for accurate testosterone/cortisol
Who Is This For?
Men over 30 experiencing low energy, reduced libido, difficulty building muscle, or mood changes. Women with irregular periods, fertility concerns, or perimenopausal symptoms. Anyone experiencing unexplained fatigue, weight gain, sleep disruption, or mood swings. Athletes interested in optimizing recovery and performance through hormonal insights.
What's Included
Preparation Required
Fasting for 10–12 hours before your appointment is recommended for accurate results (water is fine). Avoid alcohol for 24 hours and intense exercise for 12 hours before the blood draw. Morning appointments are ideal for consistent hormone and glucose readings. The blood draw typically takes 5–10 minutes.
Biomarkers Tested
10Regulates reproductive function in both sexes. In women, FSH stimulates egg development; elevated levels indicate declining ovarian reserve or menopause. In men, FSH stimulates sperm production.
The most potent and prevalent form of estrogen. In women, estradiol regulates the menstrual cycle, fertility, and bone density. In men, it's produced from testosterone and plays roles in bone health and libido. Levels vary significantly with age and menstrual cycle.
Works with FSH to regulate reproductive function. In women, an LH surge triggers ovulation. In men, LH stimulates testosterone production. Abnormal levels can indicate pituitary or gonadal disorders.
The primary screening test for thyroid function. TSH is produced by the pituitary gland to regulate thyroid hormone production. High TSH indicates an underactive thyroid (hypothyroidism), while low TSH suggests an overactive thyroid (hyperthyroidism).
The unbound, active form of the main thyroid hormone T4. Free T4 directly reflects thyroid gland output and is used alongside TSH to diagnose and monitor thyroid disorders.
A protein that binds and transports sex hormones (testosterone, estrogen) in the blood. High SHBG reduces the amount of free, active hormones available. SHBG increases with age, thyroid hormones, and estrogen; decreases with obesity and insulin resistance.
The primary stress hormone, produced by the adrenal glands. Cortisol regulates metabolism, immune response, blood pressure, and the sleep-wake cycle. Chronically elevated cortisol from stress contributes to weight gain, immune suppression, and metabolic dysfunction.
The sulfated, stable form of DHEA with a long half-life, making it the preferred test for adrenal androgen production. DHEA-S is the most abundant circulating steroid hormone and a key longevity biomarker.
The primary male sex hormone, also important in women at lower levels. Testosterone regulates muscle mass, bone density, fat distribution, libido, and mood. Levels decline naturally with age in both sexes.
The unbound, biologically active fraction of testosterone (typically 1–3% of total). Free testosterone is the form that can enter cells and exert effects. More clinically relevant than total testosterone for assessing hormonal status.
Includes a $6.00 Physician Service Fee
- Category
- Diagnostic
- Sample Type
- Blood draw
- Duration
- 30 min
- Results
- 4 days