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Quest Diagnostics Quest Diagnostics

Insulin Resistance Test Panel

Type

Blood Testing

Biomarkers

5

Duration

30 min

Results

24 hours

Comprehensive blood test to assess insulin resistance risk.

This Insulin Resistance Test Panel measures insulin and C-peptide levels in your blood to assess your risk of insulin resistance. Insulin resistance (IR) is an underlying condition when your body does not respond to insulin, causing high blood sugar levels. If insulin resistance is not identified early, it may lead to many serious health issues like prediabetes, type 2 diabetes, CVD, stroke, and more. This panel also provides a calculated score based on the insulin and C-peptide values, which is associated with a probability of insulin resistance. The panel and score help identify hidden metabolic risk, even when HbA1c and glucose (blood sugar) levels are normal. A higher score can indicate a higher risk of insulin resistance or developing a serious health issue. Knowing your risk may help you and your healthcare provider identify these issues before they become problematic.

Key Details

Biomarkers
2–4 metabolic markers
Fasting Required
Yes, 10–12 hours for fasting glucose
Sample Type
Blood draw
Turnaround
Same day to 24 hours
Common Use
Diabetes screening, insulin resistance detection

Who Is This For?

Adults over 35 as part of routine screening (diabetes affects 1 in 10 adults globally). Anyone with a family history of type 2 diabetes. People who are overweight or physically inactive. Those experiencing increased thirst, frequent urination, unexplained weight loss, or fatigue. Women with a history of gestational diabetes or polycystic ovary syndrome (PCOS).

What's Included

Fasting blood glucose
HbA1c (glycated hemoglobin)
Fasting insulin (if included in panel)
HOMA-IR insulin resistance index (if insulin included)

Preparation Required

Fasting for 10–12 hours before your appointment is recommended for accurate results (water is fine). Avoid alcohol for 24 hours and intense exercise for 12 hours before the blood draw. Morning appointments are ideal for consistent hormone and glucose readings. The blood draw typically takes 5–10 minutes.

Biomarkers Tested

5
Insulin µIU/mL

The hormone produced by the pancreas to regulate blood sugar. Elevated fasting insulin — even with normal glucose — is an early marker of insulin resistance, which precedes type 2 diabetes by years. Key biomarker in longevity medicine.

C-Peptide ng/mL

A byproduct of insulin production, released in equal amounts to insulin. C-peptide measures how much insulin your pancreas is producing, helping distinguish between type 1 and type 2 diabetes.

Insulin µIU/mL

The hormone produced by the pancreas to regulate blood sugar. Elevated fasting insulin — even with normal glucose — is an early marker of insulin resistance, which precedes type 2 diabetes by years. Key biomarker in longevity medicine.

Glucose mg/dL

Blood sugar — the body's primary energy source. Fasting glucose screens for diabetes and prediabetes. Chronically elevated glucose damages blood vessels and organs. Levels fluctuate with meals, stress, and physical activity.

HbA1c (Glycated Haemoglobin) %

Reflects your average blood sugar over the past 2–3 months by measuring the percentage of hemoglobin with attached glucose. HbA1c is the gold standard for diagnosing and monitoring diabetes, unaffected by daily fluctuations.

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Price
$99.00

+ $6.00 Physician Service Fee

Category
Diagnostic
Sample Type
Blood draw
Duration
30 min
Results
24 hours