Needle Mesotherapy (CytoCare 532)

A needle mesotherapy session using CytoCare 532 — a biorevitalising cocktail of hyaluronic acid, amino acids, vitamins, and minerals — delivered via multiple superficial micro-injections across the face to improve skin hydration, radiance, and fine line density.

Needle mesotherapy at POWAB Clinic uses CytoCare 532, a CE-marked biorevitalisation product manufactured by Revitacare (France), to deliver a targeted cocktail of active ingredients directly into the superficial dermis. CytoCare 532 combines non-cross-linked hyaluronic acid (providing intense hydration without volumising effect), a complex of 53 active ingredients including amino acids, vitamins (A, B complex, C, E), minerals (zinc, magnesium, manganese), coenzymes, and nucleic acid bases. The "532" designation refers to this specific 53-ingredient complex at a defined concentration, formulated to nourish the dermis from within and stimulate cellular metabolic activity. The treatment is delivered via a series of superficial intradermal injections using a fine 30- or 32-gauge needle. The practitioner performs a nappage technique — rapid, closely spaced micro-injections depositing small volumes (0.01-0.02ml) of the product at approximately 1-2mm depth across the treatment area. This creates a blanket of hydration and active ingredients throughout the dermal layer, unlike topical application which is largely blocked by the epidermal barrier. Common treatment zones include the full face, neck, and decolletage. The procedure takes approximately 30 minutes. Topical anaesthetic cream is applied beforehand to minimise discomfort, though the injections are generally well-tolerated due to the superficial depth and fine needle gauge. Post-treatment, the skin may show small wheals (raised bumps) at each injection site that flatten within 2 to 4 hours, along with mild redness that resolves within 24 hours. There is minimal meaningful downtime — most patients resume normal activities the same day. A course of 3 to 4 sessions spaced 2 to 3 weeks apart is recommended for the initial intensive phase, followed by maintenance treatments every 1 to 2 months. Patients typically notice improved skin luminosity and hydration after the first session, with progressive improvement in fine lines, skin elasticity, and overall radiance across the course. Mesotherapy is often combined with other treatments in the POWAB menu — for example, a mesotherapy course between botox or filler appointments to maintain skin quality between injectable sessions.