Mesotherapy

Mesotherapy at Poliklinika Sever's Eye Care & Aesthetics Centre involves the intradermal microinjection of active ingredients — vitamins, hyaluronic acid, amino acids, antioxidants, or peptides — directly into the target skin layer using fine needles or a mesotherapy gun. Performed by MUDr. Kim Štěpánková FEBO DiS., the technique bypasses the skin's epidermal barrier to deliver concentrated active substances precisely where collagen remodelling and hydration are needed. At 1,000–2,000 Kč per ampule depending on the product selected, mesotherapy at this clinic is positioned as a scientifically grounded skin rejuvenation and hair-restoration adjunct, commonly combined with botulinum toxin or filler treatments for a comprehensive facial refreshment.

Mesotherapy was developed by French physician Dr. Michel Pistor in the 1950s as a technique for delivering therapeutic substances directly into the mesoderm — the middle layer of tissue — via multiple superficial microinjections. In aesthetic medicine, the principle is applied to the face, neck, décolleté, and scalp to deliver active ingredients at the precise depth where they can be most effective, circumventing the epidermal barrier that limits the penetration of topically applied serums. At the Eye Care & Aesthetics Centre (Centrum oční péče a estetiky) at Poliklinika Sever, mesotherapy is administered by MUDr. Kim Štěpánková, FEBO DiS. The physician selects the appropriate product or combination based on the clinical objective: **Facial skin rejuvenation:** Cocktails containing hyaluronic acid fragments, vitamins (B-complex, C, biotin), antioxidants (glutathione, DMAE), and collagen-stimulating amino acids are injected into the superficial dermis using a fine needle (typically 4–13mm depth depending on the target layer and body site). The microinjections trigger a controlled wound-healing response — collagen induction — alongside the direct biological effect of the active ingredients. Patients typically notice improved skin luminosity and hydration after 3–5 sessions, with longer-term firmness improvement over 3–6 months of a regular protocol. **Scalp and hair mesotherapy:** Active ingredients including minoxidil, biotin, finasteride (where indicated), zinc, and growth-factor peptides can be injected directly into the scalp mesoderm to improve blood supply to hair follicles, extend the anagen (growth) phase, and reduce miniaturisation in androgenetic alopecia. Results vary by patient but are typically observable after 6–10 sessions. **Eye contour and periorbital rejuvenation:** Given MUDr. Štěpánková's ophthalmology specialisation, the periocular region — tear trough, crow's feet, under-eye skin — is an area where her anatomical precision is a clinical advantage. Lightweight hyaluronic acid and peptide cocktails can be injected into the fine skin around the eyes with reduced risk of complications compared to less experienced practitioners. The session involves thorough cleansing of the treatment area, optional application of topical anaesthetic cream (30 minutes before), and injection of the selected ampule (1–2 ml) across the target zone using either a single needle in a 'nappage' technique (multiple overlapping microinjections) or a mesotherapy gun for faster, consistent delivery. Sessions last 30–45 minutes including preparation; mild redness and small injection-site papules resolve within 24–48 hours. Bruising is possible and minimised by avoiding blood-thinning agents before treatment. A course of 3–6 sessions is typically recommended for facial rejuvenation, followed by a maintenance session every 2–3 months. Pricing of 1,000–2,000 Kč per session reflects the product quality — pharmaceutical-grade mesotherapy cocktails are more expensive than commodity preparations. The initial consultation (200 Kč, credited to treatment) determines the product and protocol appropriate for the patient's skin type and goals.