Type
Blood Testing
Biomarkers
11
Duration
30 min
Results
24 hours
Sample
Blood (venous draw)
What's included
8 deliverables in this treatment
- CA 125 — primary ovarian cancer marker
- HE4 — high-specificity ovarian cancer marker (ROMA algorithm partner)
- CA 15-3 — breast cancer monitoring marker
- CA 19-9 — pancreatic and GI cancer marker
- CEA — colorectal and lung cancer marker
- AFP — liver and germ cell tumour marker
- All 6 markers on Abbott Alinity ii / DPC Immulite 2000XPi (SEKK accredited)
- Printed and electronic results same or next working day
A six-marker oncological surveillance panel for women, covering the key gynecological cancer markers (CA 125, CA 15-3, HE4), the gastrointestinal markers (CA 19-9, CEA), and AFP (liver and germ cell). HE4 combined with CA 125 in the ROMA algorithm significantly improves ovarian cancer risk classification compared with CA 125 alone. All markers run on Abbott Alinity ii or DPC Immulite 2000XPi at PKBH Olomouc under SEKK external quality control.
About this treatment
Ovarian, breast, and gastrointestinal cancers together account for the majority of cancer mortality in women, and each of these has a serum marker with clinical utility when interpreted correctly. A comprehensive six-marker panel provides a broad surveillance signal that no single test could achieve — while also documenting a personal baseline from which future changes can be measured.
Markers included: - CA 125 (cancer antigen 125) — the primary ovarian cancer marker. Elevated in around 80% of advanced epithelial ovarian cancers; also elevated in endometriosis, fibroids, pelvic inflammatory disease, and early pregnancy — making baseline and trend interpretation important. Measured on Abbott Alinity ii, priced at 548 Kč. - HE4 (human epididymis protein 4) — a newer ovarian cancer marker with higher specificity than CA 125, particularly…
All six markers are immunochemistry assays run on the SEKK-accredited Abbott Alinity ii and DPC Immulite 2000XPi platforms at PKBH's Olomouc central laboratory. R3 Audit certification covers the full laboratory.
Good to know
- Biomarkers
- 6 (CA 125, HE4, CA 15-3, CA 19-9, CEA, AFP)
- Analyser
- Abbott Alinity ii + DPC Immulite 2000XPi
- Results
- Same day / next morning
- Referral needed
- No — walk-in self-pay
- ROMA algorithm
- CA 125 + HE4 combined for ovarian risk
Who is this for?
Women over 40 with family history of gynecological or GI cancer, endometriosis, unexplained pelvic symptoms, breast or ovarian cancer monitoring
Preparation required
No fasting required. Defer CA 125 if pregnancy is possible (false elevation). Walk in from 07:00 at any PKBH Olomouc site — no referral or appointment needed.
Panel categories
Biomarkers tested
11A biomarker associated with some breast cancers; used to monitor treatment response in patients with metastatic breast cancer.
A biomarker commonly used in the diagnosis and management of pancreatic and gastrointestinal cancers. Elevated levels can also be found in other conditions such as liver disease.
Tumor marker; elevated levels may indicate certain cancers, particularly gastrointestinal cancers.
The cortisol awakening response (CAR) is a period of increased cortisol secretory activity initiated by morning awakening and typically peaking between 30 and 45min post awakening
Measures only the unbound PSA in the blood.
Imbalances in gut pH influence short-chain fatty acid production and their effects.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
PKBH is led by MUDr. Milada Popotrandovská as director, with analytical operations headed by RNDr. Ivana Slouková and quality management overseen by Mgr. Vojtěch Mutina. The haematology department is supervised by MUDr. Jaromír Hubáček and doc. MUDr. Jaroslav Bačovský, CSc. Metrological oversight is held by RNDr. Kateřina Mutinová, and the Prostějov site is headed by doc. MUDr. Josef Bartek, CSc. All laboratory…
Languages: cs
Treatment highlights
- CA 125 — primary ovarian cancer marker
- HE4 — high-specificity ovarian cancer marker (ROMA algorithm partner)
+6 more items in What's included
Approx. 2,675 Kč per panel (CA 125 548 + CA 15-3 548 + CA 19-9 548 + HE4 548 + CEA 202 + AFP 206 Kč = 2,600 Kč, plus 75 Kč venous draw and serum separation). Tests billed à la carte at published PKBH self-pay rates. No online booking — walk-in only; no appointment required. Results same or next working day.