Profhilo — Bioremodeling (1 session)

Profhilo bioremodeling injection (2 ml) — high-concentration, thermally stabilised HA that hydrates deeply and biostimulates collagen and elastin across all skin layers without adding volume.

Perfect Clinic offers Profhilo bioremodeling at 7,900 CZK per session (approximately 316 EUR), using the Bio Aesthetic Points (BAP) protocol — five precisely mapped injection points per side of the face that maximise the HA's radial tissue distribution from a minimal number of entry points. This precision placement minimises discomfort and reduces the risk of localised whealing that can occur with less targeted injection maps. Profhilo Structura, the newer variant designed for areas of greater skin laxity (neck, décolleté, upper arms), is also available at 11,900 CZK per session — a higher-G-prime formulation that provides slightly more structural support in zones with less intrinsic tissue tone. The clinic's dermatologist recommends between the two variants based on the patient's specific concerns and the target treatment area. At Perfect Clinic, Profhilo is commonly used as a standalone bioremodeling treatment for patients in their 30s to 50s experiencing the early signs of skin quality decline — reduced elasticity, a slightly crepey texture, loss of the dewy luminosity of younger skin — without the volume loss or structural change that warrants fillers. It is also used as a complement to injectable volumising treatments: by improving the quality and thickness of the dermis, Profhilo makes the skin a better substrate for fillers, allowing them to sit more naturally and last longer. The five-point injection technique takes approximately 15 minutes after the physician assessment. Patients can return to normal activities immediately. Small raised wheals at the injection points resolve within 24 hours. Full collagen and elastin biostimulation results develop over four to eight weeks after each session, with the recommended primary course of two sessions spaced four weeks apart.