Type
Blood Testing
Biomarkers
8
Duration
15 min
A standard lipid profile measuring total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, and the total-to-HDL ratio. Provides the core cardiovascular risk markers used in clinical guidelines to assess and monitor heart disease risk.
Cardiovascular disease remains the leading cause of death in the Netherlands, and lipid levels are among the most modifiable risk factors. This panel measures the four core lipid markers plus their clinically important ratio, providing the foundation for cardiovascular risk assessment that underpins European and Dutch clinical guidelines. Total cholesterol provides a broad overview, but the individual components carry the clinical weight. LDL cholesterol — often described as the atherogenic fraction — is the primary target of intervention in most cardiovascular risk models. HDL cholesterol is associated with reverse cholesterol transport and is generally considered protective. Triglycerides, when elevated, contribute independently to cardiovascular risk and are often associated with insulin resistance, metabolic syndrome, and dietary factors. The total-to-HDL ratio distils these numbers into a single metric that many clinicians consider more predictive than any individual value. Fasting is not strictly required for modern lipid panels, but non-fasting triglyceride values may be elevated after a meal. For the most clinically useful results, a fasting draw — no food for 10 to 12 hours, water permitted — is recommended. This panel is suitable as a standalone cardiovascular risk screen or as a follow-up to monitor the effect of dietary changes, exercise, or lipid-lowering medication.
Key Details
- Biomarkers
- 5
- Results
- Next business day
- Focus
- Cardiovascular risk
- Lab
- ISO 15189 certified
Who Is This For?
Cardiovascular risk assessment, cholesterol monitoring, metabolic health screening, follow-up after dietary or lifestyle changes
What's Included
Panel Categories
Biomarkers Tested
8The main protein component of HDL cholesterol particles. Higher ApoA1 levels reflect more HDL particles and are associated with lower cardiovascular risk. The ApoB/ApoA1 ratio is a powerful predictor of heart disease.
The primary protein on LDL and VLDL particles. Each atherogenic lipoprotein particle carries exactly one ApoB molecule, making it a direct measure of the number of particles that can enter artery walls. Considered a superior predictor of cardiovascular risk compared to LDL cholesterol.
Often called 'good' cholesterol, HDL carries cholesterol away from arteries back to the liver for removal. Higher HDL levels are protective against heart disease. Exercise, healthy fats, and moderate alcohol intake can raise HDL.
Often called 'bad' cholesterol, LDL deposits cholesterol in artery walls, contributing to plaque buildup and atherosclerosis. LDL is the primary target for cardiovascular risk reduction through diet, exercise, and medication.
Lp(a) is a cholesterol-carrying particle linked to genetic risk for heart disease. High levels increase cardiovascular risk.
The combined measure of all cholesterol in your blood, including HDL, LDL, and VLDL. While useful as an overview, the breakdown between HDL and LDL is more clinically meaningful for assessing cardiovascular risk.
The most common type of fat in the body, stored for energy. Elevated triglycerides — often from excess sugar, alcohol, or calories — increase cardiovascular risk and can cause pancreatitis at very high levels.
