IV Drip — NAD+ 250mg

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in every cell of the body, essential for mitochondrial energy production, DNA repair, and the activity of sirtuin enzymes — a family of proteins implicated in cellular ageing and stress response. NAD+ levels naturally decline with age, and research has explored whether replenishing NAD+ through supplementation or infusion may support cellular health and longevity markers.

The 250mg dose at One Thirty Labs is the standard-strength NAD+ protocol, delivered intravenously over approximately 180 minutes (three hours). The extended duration is necessary because NAD+ infusions commonly cause a flushing, warming, or chest-tightening sensation if administered too quickly — a well-known side effect that resolves by slowing the drip rate. Clients should expect to spend the full three hours in the studio.

Intravenous delivery of NAD+ achieves plasma concentrations that oral NAD+ precursors (such as NMN or NR) may not match, though the comparative clinical significance of different delivery routes continues to be studied. Published research on NAD+ replenishment has explored effects on mitochondrial function, cognitive performance, muscle recovery, and biomarkers of ageing — though most human studies remain small and the field is evolving.