Coagulation (Clotting) Blood Test
Type
Blood Testing
Biomarkers
5
Duration
30 min
Results
24 hours
This test identifies problems with clotting factors causing excessive or insufficient blood clotting.
A coagulation panel measures how well your blood clots — a critical balance between stopping bleeding and preventing dangerous clots. The panel typically includes PT/INR (prothrombin time, measuring the extrinsic clotting pathway), aPTT (activated partial thromboplastin time, measuring the intrinsic pathway), fibrinogen (the protein that forms the structural framework of blood clots), and D-dimer (a marker of clot breakdown that can indicate active clotting). These tests are essential for monitoring anticoagulant therapy (warfarin, heparin), evaluating unexplained bleeding or bruising, and screening for clotting disorders like Factor V Leiden or antiphospholipid syndrome.
Key Details
- Biomarkers
- 3–6 clotting markers
- Fasting Required
- No
- Sample Type
- Blood draw
- Turnaround
- Same day to 24 hours
- Common Use
- Anticoagulant monitoring, clotting disorder screening
Who Is This For?
People taking blood-thinning medications (warfarin, heparin) who need regular monitoring. Anyone with unexplained bruising, prolonged bleeding, or a history of blood clots. Women with recurrent miscarriages, which can be caused by clotting disorders. People with a family history of deep vein thrombosis (DVT) or pulmonary embolism.
What's Included
Preparation Required
Fasting for 10–12 hours before your appointment is recommended for accurate results (water is fine). Avoid alcohol for 24 hours and intense exercise for 12 hours before the blood draw. Morning appointments are ideal for consistent hormone and glucose readings. The blood draw typically takes 5–10 minutes.
Biomarkers Tested
5An enzyme found in the liver, heart, and muscles. While less liver-specific than ALT, elevated AST can indicate liver damage, heart attack, or muscle injury. The AST/ALT ratio helps distinguish between different liver conditions.
Activated partial thromboplastin time ratio — measures how long it takes blood to clot through the intrinsic pathway. Used to monitor heparin therapy and detect clotting factor deficiencies or lupus anticoagulant.
A protein essential for blood clotting that also serves as an inflammation marker. Elevated fibrinogen increases blood viscosity and clot risk, contributing to cardiovascular disease independent of cholesterol levels.
Ratio of the patient's prothrombin time (PT) to a control PT.
Measures the time it takes for blood plasma to clot after adding a tissue factor that activates the extrinsic pathway of coagulation.
- Category
- Diagnostic
- Sample Type
- Blood draw
- Duration
- 30 min
- Results
- 24 hours
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