Exercise with Oxygen Therapy (EWOT)

Exercise with Oxygen Therapy (EWOT) is an advanced oxygen training modality offered at O2genes that combines physical exercise with precisely alternating oxygen concentrations to produce a training adaptation distinct from either standard exercise or pure hyperoxic breathing alone. The protocol uses a Hyperoxia-Hypoxia Concentrator that rapidly switches between delivering high-concentration (hyperoxic) air and low-oxygen (hypoxic) air during a single…

The mechanism behind EWOT's benefits lies in the hormetic stress response triggered by alternating between oxygen surplus and deficit. During the hyperoxic phase, tissues are saturated with oxygen and blood vessels dilate; during the hypoxic phase, the body responds by releasing nitric oxide, activating hypoxia-inducible factor (HIF-1α), and stimulating erythropoietin (EPO) production — biological signals that promote angiogenesis (growth of new blood…

Clients exercising on a stationary bike, treadmill, or other aerobic equipment while breathing through the EWOT mask experience measurable improvements in physical endurance and stamina, faster post-workout recovery through reduced lactic acid accumulation, and enhanced mental clarity and cognitive function. The therapy also supports cellular regeneration and skin health at a systemic level, and is particularly appealing to athletes, executives managing…