Inflammation & Hormonal Stress Panel (DUTCH)

Chronic inflammation and hormonal dysfunction are deeply intertwined biological processes. Elevated cortisol suppresses immune function and drives visceral fat accumulation, itself a source of inflammatory cytokines. Oestrogen imbalance promotes chronic low-grade inflammation via multiple pathways. Testosterone deficiency correlates with elevated CRP and IL-6. Understanding inflammation fully requires simultaneously measuring the hormonal drivers — and…

NutraNourish's Inflammation and Hormonal Stress Panel combines the DUTCH Complete test with a targeted inflammatory blood panel. The DUTCH panel — using dried urine samples collected at home across a single day — provides unparalleled detail on the hypothalamic-pituitary-adrenal (HPA) axis: not just total cortisol but the cortisol awakening response, free cortisol metabolites (capturing cortisol production), and cortisone — distinguishing between high…

Estrogen metabolism is mapped across three pathways — 2-OH, 4-OH, and 16-OH oestrogens — with particular attention to the 4-OH pathway, which is genotoxic and associated with elevated breast and endometrial cancer risk when dominant. DHEA and its metabolites, progesterone metabolites, and androgens including testosterone metabolites are fully characterised.