Needle Mesotherapy NCTF135 — Face

Intradermal microinjections of NCTF135 — a polyrevitalising cocktail containing 55 active ingredients including hyaluronic acid, vitamins, amino acids, minerals, and coenzymes — delivered directly into the facial dermis to revitalise, hydrate, and improve skin quality from within.

NCTF135 (New Cellular Treatment Factor) is a CE-marked polyrevitalising solution manufactured by Filorga, containing 55 bio-active ingredients in a precisely formulated cocktail: non-crosslinked hyaluronic acid for hydration, 12 vitamins (A, B-complex, C, E) for antioxidant defence and cellular metabolism, 23 amino acids as building blocks for collagen and elastin synthesis, 6 minerals (zinc, magnesium, calcium, iron, copper, manganese) as enzymatic cofactors, 6 coenzymes for energy production in fibroblasts, and nucleic acid bases for DNA repair. This broad-spectrum formulation aims to provide fibroblasts with the complete nutritional substrate they need for optimal function. At Neonia, NCTF135 is administered via manual needle mesotherapy — the practitioner uses a fine-gauge needle (30-32G) or mesotherapy gun to deliver multiple superficial microinjections directly into the papillary dermis at a depth of 1-2mm. The injection technique follows a systematic nappage pattern across the entire face, placing micro-deposits of the solution approximately 1cm apart. This ensures uniform distribution of the active ingredients throughout the treatment area. The treatment takes approximately 30 minutes. Topical anaesthetic cream may be applied beforehand for comfort. During the procedure, patients feel a series of tiny pricks — individually minor but cumulatively noticeable. Immediately after treatment, the face appears slightly red with visible injection points (tiny papules), which typically resolve within 12-24 hours. Mild bruising is possible, particularly around the delicate eye area. The NCTF135 protocol at Neonia typically involves an initial intensive course of 3-6 sessions spaced 2-4 weeks apart, followed by maintenance sessions every 1-3 months. Patients report progressive improvement in skin luminosity, hydration, firmness, and fine line softness over the course of treatment. Needle mesotherapy is particularly valued for treating dull, dehydrated, or stressed skin, smoker's skin, early ageing signs, and as a complement to other rejuvenation procedures such as botox, fillers, or laser treatments.