Rejuran (Salmon DNA Skin Rejuvenation)

Rejuran is a skin rejuvenation treatment using PDRN (polydeoxyribonucleotide) — salmon-derived DNA fragments that are biologically compatible with human tissue. Applied via mesotherapy micro-injections, PDRN activates skin cell repair pathways to rebuild the skin's structural integrity from within. Neo Beauty Clinic documented ten clinical effects: lifting, pore minimisation, pigmentation reduction, texture refinement, tone evening, fine line reduction, skin barrier regeneration, dead cell removal, sebum regulation and confirmed clinical safety. Separate formulations are available for the eye area (Rejuran i) and the full face (Rejuran Healer), with discounted multi-session packages.

Rejuran works through PDRN (polydeoxyribonucleotide), a biocompatible compound derived from salmon sperm DNA that shares structural similarity with human DNA. When introduced into the dermis via micro-injections, PDRN binds to adenosine A2A receptors in skin cells, stimulating collagen and elastin synthesis, reducing inflammation and promoting the regeneration of the extracellular matrix — the scaffolding that gives skin its firmness and elasticity. Neo Beauty Clinic identifies ten documented effects of the treatment: skin lifting, pore size reduction, pigmentation improvement, surface texture refinement, tone evening, fine line softening, skin barrier regeneration, accelerated turnover of damaged cells, normalised sebum production and a confirmed clinical safety profile — making it suitable for sensitive skin types and those who want a biologically active alternative to botulinum toxin or conventional fillers. Two product variants are offered: - **Rejuran Healer** — formulated for the full face, neck and broader skin areas. Single application 9,500 Kč; two applications 15,500 Kč; four-session course 28,000 Kč. - **Rejuran i Eye** — a lighter, more fluid formulation designed for the delicate periorbital zone. Single 6,500 Kč; two-pack 12,500 Kč; three-pack 17,500 Kč. The procedure begins with skin assessment, followed by a skin consultation to agree on areas and protocol. Micro-needle mesotherapy delivers the product into the dermis. Mild redness or small wheals at injection points resolve within hours. No extended downtime is required. Recommended ideal candidates include post-acne skin, UV-damaged or sun-aged skin, and anyone seeking a collagen-stimulating treatment without synthetic fillers. One patient at Neo Beauty Clinic described the session as 'nearly painless' with a relaxation mask provided during recovery — a practical detail that sets the experience apart from a purely clinical environment.