GOURI Liquid Lifting (PCL Biostimulator)

GOURI is a next-generation liquid lifting treatment using polycaprolactone (PCL) — a biodegradable polymer — delivered through a fine cannula throughout the face to stimulate long-term collagen production. Unlike conventional fillers that add volume to specific points, GOURI spreads evenly beneath the skin via the patented CESABP technology to create a global firming and tightening effect. Neo Beauty Clinic applies the treatment in approximately twenty minutes, with visible initial improvement after twenty-four hours and the full collagen-building effect developing over two to three months. One session per year is the typical maintenance protocol.

GOURI uses polycaprolactone (PCL), a synthetic biodegradable polymer also used in absorbable sutures, as a biostimulatory agent. When introduced into the facial soft tissue via a very fine cannula, GOURI's patented CESABP (Controlled Enzyme-Sensitive Amino-Biphasic Polymer) technology allows the liquid PCL to distribute broadly beneath the skin surface rather than localising at a single injection point. As the body gradually absorbs the PCL over months, fibroblasts in the surrounding tissue are stimulated to synthesise new collagen and elastin, progressively firming and tightening the skin. At Neo Beauty Clinic, the appointment begins with a physician consultation and skin assessment. The GOURI is then introduced through a single or limited number of cannula entry points that allow the liquid to travel through the facial tissue planes. The procedure takes around twenty minutes. Timeline of results: partial improvement is often visible within twenty-four hours as initial tissue response begins; the full firming and lifting benefit continues developing over the following two to three months as new collagen matures. A single annual session is typically sufficient to maintain results, making GOURI a low-maintenance option relative to treatments requiring multiple sessions. Important: GOURI should not be combined with botulinum toxin injections or hyaluronic acid fillers on the same day, as interaction can affect distribution. Post-treatment, avoid sauna, solarium and wellness facilities for two weeks, and skip alcohol and coffee on treatment day to minimise vascular effects. GOURI is not suitable during pregnancy.