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Neo Beauty Clinic — Rejuran treatment room

Biostimulatory Fillers (Profhilo & Nucleofill)

Type

Botox & Fillers

Duration

30 min

What's included

4 deliverables in this treatment

  • Physician selection of appropriate product (Profhilo or Nucleofill variant)
  • Injection using BAP (Bio Aesthetic Points) or mesotherapy technique
  • Post-procedure soothing treatment
  • Protocol planning for optimal multi-session course

Biostimulatory fillers — Profhilo and Nucleofill — are a category of injectable skin treatment that works by stimulating the skin's own collagen and elastin rather than simply adding volume. Profhilo contains an unusually high concentration of hyaluronic acid (64 mg/2 ml) that spreads broadly through the dermis once injected, delivering intense hydration and activating four types of collagen simultaneously. Nucleofill uses PDRN technology, the same salmon-derived DNA complex found in Rejuran, to repair and regenerate skin cells from within. Neo Beauty Clinic offers both products across face, neck and décolletage.

About this treatment

Biostimulatory fillers represent a distinct category between conventional HA dermal fillers (which add volume) and skin boosters (which focus on surface hydration). Their primary mechanism is cellular — they activate the skin's own fibroblasts to produce new structural proteins rather than passively filling tissue.

Profhilo (7,000 Kč / 2 ml; two-session protocol 12,500 Kč)

Contains a very high concentration of ultra-pure hyaluronic acid (approximately 64 mg per 2 ml) without any chemical cross-linking agents. This 'free' HA disperses rapidly through tissue planes after injection via just five injection points per side (the BAP — Bio Aesthetic Points — technique), migrating broadly rather than staying localised. It simultaneously stimulates four types of collagen (I, III, IV and VII) and two types of elastin, produces deep…

Good to know

Profhilo HA concentration
~64 mg / 2 ml — unusually high
Nucleofill technology
PDRN — salmon-derived DNA repair
Effect
Collagen + elastin stimulation, deep hydration

Who is this for?

Lax, dehydrated or crepey skin on the face, neck or décolletage needing structural regeneration rather than volume

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

Clinical team

The clinic is staffed by five licensed physicians. MUDr. Gabriel Badida is a plastic surgeon specialising in blepharoplasty, brow lifting, botulinum toxin and fillers; he also practises at University Hospital Olomouc. MUDr. Nela Krzoková is a plastic surgeon and member of the Czech Hand Surgery Society, focusing on natural results and minor surgical procedures. MUDr. Pavlína Štastná is an aesthetic medicine…

Languages: Czech

What clients say

"{"author":"Miriam","date":"2025-10-13","procedure":"Rejuran","text":"Excellent explanation, constant communication throughout, nearly painless, and recovery included a relaxation mask — a great experience."}"

"{"author":"Lenka","date":"2026-03-04","procedure":"Botulinum toxin","text":"Great thanks to Dr. Štastná and the nurse for their professional and empathetic approach. Very satisfied."}"

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