Heart & Metabolic Health Check

A focused 5-biomarker cardiovascular and metabolic risk panel measuring apolipoprotein B, homocysteine, HbA1c, fasting insulin, and high-sensitivity CRP. These five markers represent the cutting edge of cardiometabolic risk assessment, going far beyond standard cholesterol testing.

The Heart and Metabolic Health Check distills cardiovascular and metabolic risk assessment to the five markers that longevity medicine practitioners consider most important. Apolipoprotein B measures the number of atherogenic particles — a more accurate predictor of heart attack risk than LDL cholesterol, which measures particle content rather than count. Homocysteine is an independent cardiovascular risk factor that also reflects B vitamin metabolism and methylation capacity. Elevated levels are associated with increased risk of stroke, heart attack, and cognitive decline, and are modifiable through targeted B vitamin supplementation. HbA1c provides a three-month average of blood sugar control, while fasting insulin reveals insulin resistance that can precede diabetes by a decade or more. Together, they provide the most complete picture of glucose metabolism available from standard blood testing. High-sensitivity CRP measures the systemic inflammation that drives atherosclerosis and metabolic dysfunction. At just five markers, this panel is remarkably information-dense — each biomarker carries significant predictive power for the conditions that cause the majority of premature deaths in Australia.