Type
Blood Testing
Biomarkers
10
Duration
15 min
Results
48 hours
A 50-biomarker longevity-focused panel assessing insulin resistance, cardiovascular risk, thyroid balance, and stress response. Adds apolipoprotein B, fasting insulin, full thyroid function, and cortisol to the baseline longevity markers — targeting the mechanisms that accelerate biological ageing.
The Advanced Longevity Panel goes beyond standard health screening to target the specific biological mechanisms that drive accelerated ageing. Fasting insulin and glucose together enable HOMA-IR calculation — the gold standard for detecting insulin resistance, which underpins metabolic syndrome and is increasingly linked to Alzheimer's disease, cancer risk, and cardiovascular events. Apolipoprotein B measures the actual number of atherogenic particles in your blood, providing a more accurate assessment of cardiovascular risk than LDL cholesterol alone. Research from the Framingham Heart Study and others has established ApoB as a superior predictor of heart attack and stroke risk. The full thyroid panel (TSH, free T3, free T4) reveals thyroid function beyond what a TSH-only test can show. Subclinical thyroid dysfunction affects metabolic rate, body composition, mood, and cognitive performance — all factors that influence both healthspan and quality of life. Cortisol rounding out the panel provides insight into the stress response system that, when chronically elevated, drives inflammation and accelerates biological ageing. Optional hormone add-ons ($35 each) allow expansion into reproductive and growth hormones for a more complete endocrine picture.
Key Details
- Biomarkers
- 50
- Results
- 24-48 hours
- Key markers
- ApoB + insulin + thyroid + cortisol
Who Is This For?
Longevity optimisation, insulin resistance screening, cardiovascular risk assessment, anti-ageing strategy
What's Included
Preparation Required
Fast for 10-12 hours. Morning blood draw (before 10am) recommended for accurate cortisol results.
Panel Categories
Biomarkers Tested
10Metabolite of estradiol.
The primary stress hormone, produced by the adrenal glands. Cortisol regulates metabolism, immune response, blood pressure, and the sleep-wake cycle. Chronically elevated cortisol from stress contributes to weight gain, immune suppression, and metabolic dysfunction.
Precursor to other hormones
Metabolite of testosterone.
Reflects your average blood sugar over the past 2–3 months by measuring the percentage of hemoglobin with attached glucose. HbA1c is the gold standard for diagnosing and monitoring diabetes, unaffected by daily fluctuations.
An amino acid produced during protein metabolism. Elevated homocysteine is an independent risk factor for cardiovascular disease, stroke, and cognitive decline. Levels are lowered by adequate B12, folate, and B6 intake.
A highly sensitive test for low-grade chronic inflammation linked to cardiovascular disease risk. Lower hs-CRP values are associated with better cardiovascular outcomes.
A hormone produced mainly by the liver in response to growth hormone. IGF-1 mediates many of growth hormone's effects on tissue growth and repair. It's more stable than GH, making it a better marker for growth hormone status.
The hormone produced by the pancreas to regulate blood sugar. Elevated fasting insulin — even with normal glucose — is an early marker of insulin resistance, which precedes type 2 diabetes by years. Key biomarker in longevity medicine.
The best indicator of overall vitamin D status. Vitamin D is essential for calcium absorption, bone health, immune function, and mood regulation. Deficiency is extremely common, especially in northern latitudes, and linked to increased disease risk.
- Category
- Diagnostic
- Sample Type
- Blood (venous draw)
- Duration
- 15 min
- Results
- 48 hours