Male Health 40+ Check-Up Panel

A targeted diagnostic panel for men aged 40 and above, combining cardiovascular and metabolic blood markers with a comprehensive male hormone assessment — testosterone, free testosterone, SHBG, DHEA-S, prolactin, and PSA. Medianna Clinic's Male Health 40+ panel is designed to identify the hormonal and metabolic shifts that are common in this age group but frequently missed in standard check-ups: declining testosterone, subclinical thyroid dysfunction, early metabolic syndrome, and prostate health indicators. The panel includes a physician consultation to contextualise findings and outline an evidence-based response.

The decade between 40 and 50 is when most men begin to experience clinically meaningful changes in hormonal and metabolic function. Total testosterone declines at roughly 1–2% per year from the mid-30s; by 45, many men have free testosterone levels that impair muscle maintenance, cognitive sharpness, libido, and mood — yet these changes often go undetected because symptoms are attributed to stress or ageing. Metabolic syndrome (abdominal obesity, insulin resistance, dyslipidaemia, hypertension) is also increasingly prevalent in this age group and substantially elevates cardiovascular risk if not detected early. Medianna Clinic's Male Health 40+ panel addresses both dimensions comprehensively. The hormone block covers: total testosterone and calculated free testosterone, SHBG (sex hormone binding globulin) to determine bioavailability of testosterone, DHEA-S (an adrenal androgen precursor that reflects adrenal reserve), LH and FSH (pituitary hormones that help distinguish primary from secondary hypogonadism), prolactin (elevated levels suppress testosterone and are associated with pituitary adenoma), and PSA (prostate-specific antigen, the primary prostate health marker, recommended annually from age 45). The metabolic block includes fasting glucose, HbA1c, full lipid profile, TSH, full blood count, liver and kidney function markers, and ferritin. **Who benefits most:** Men aged 40–65 noticing fatigue, reduced muscle mass, mood changes, reduced libido, or weight gain who want objective data rather than assumptions. Also valuable as a baseline for men who train seriously and want to monitor hormonal health, and for those considering testosterone replacement therapy who need a full pre-treatment screen. **Session protocol:** Fasting blood draw in the morning (testosterone is highest in the morning — afternoon samples can underestimate levels by 15–20%). Physician consultation included in the fee reviews all results, puts hormone levels in age-appropriate context, and outlines the options — lifestyle modification, supplementation, or specialist referral if indicated. **Preparation:** Book a morning appointment (before 10:00 is ideal for testosterone). Fast 8–10 hours. Avoid alcohol for 48 hours before. **Aftercare:** Eat a meal after the blood draw. The physician will advise on any markers outside the normal range and whether endocrinology or urology follow-up is appropriate. **Privacy:** All results are held in strict medical confidence.