Glow-Up — Skin & Hair Beauty Infusion

A targeted intravenous infusion formulated to nourish skin, hair, and nails from the inside out, delivering a concentrated blend of antioxidants, collagen cofactors, and skin-supportive vitamins directly into the bloodstream. The Glow-Up (also known as Beauty Reset) protocol at Medianna Clinic combines high-dose Vitamin C — the critical cofactor in collagen synthesis — with biotin, glutathione, and B-complex vitamins that support keratinocyte health and reduce oxidative damage to dermal structures. Results are typically visible as improved skin radiance and texture within one to two weeks of the first session.

Skin ageing, hair dullness, and brittle nails share a common biochemical root: declining collagen production, oxidative stress from free radicals, and micronutrient depletion that impairs the cells responsible for skin and hair maintenance. Topical creams address the surface; intravenous nutrient delivery targets the deeper dermal and follicular layers where these processes originate. Medianna Clinic's Glow-Up infusion (Beauty Reset) is a physician-reviewed protocol built around the biochemistry of connective tissue and skin health: high-dose vitamin C as the rate-limiting cofactor in collagen type I and III synthesis (the structural proteins of skin, hair follicles, and nails), glutathione — the body's primary intracellular antioxidant — which protects keratinocytes and melanocytes from oxidative damage and may contribute to skin brightness, biotin (B7) which is essential for keratin synthesis and is associated with improved hair thickness and reduced breakage, B-complex vitamins (B2, B3, B5, B6) supporting energy metabolism within rapidly dividing skin cells, and magnesium for cellular hydration and enzymatic function. **Who benefits most:** People experiencing dull or dehydrated skin, hair shedding or loss of shine, nail brittleness, or recovery from a period of poor nutrition, illness, or high stress. Popular among those preparing for weddings, events, or photo shoots, and those on restrictive diets that limit micronutrient intake. **Session protocol:** A physician consultation screens for skin conditions, medications, and current skincare regimen. The IV drip runs for 45–60 minutes. Some clients note a mild warmth or skin flushing from the niacin component — this is transient. Visible improvements in skin radiance are typically noticeable within 7–14 days; hair changes take 4–8 weeks as the hair growth cycle responds. **Frequency:** Monthly sessions for maintenance; a course of three consecutive monthly sessions is recommended for visible hair improvement. Can be combined with the clinic's INNO-TDS hair mesotherapy for a comprehensive hair restoration programme. **Aftercare:** Increase water intake for 24 hours after the infusion. Use SPF daily — the infusion increases skin sensitivity to UV. Avoid alcohol for 24 hours. **Safety:** Safe for most adults. Inform the physician of any known glutathione sensitivity, G6PD deficiency (relevant for high Vitamin C dosing), or currently prescribed retinoids.