


Type
Microneedling
Duration
1 hour
What's included
3 deliverables in this treatment
- Numbing cream application (30–45 min prior)
- Physician-performed Dermapen microneedling session
- Exosome serum application (included in exosome variant)
Dermapen microneedling at MarBelle Clinic uses a motorised Dermapen device to create thousands of micro-perforations across the treatment surface, triggering the skin's natural wound-healing response — specifically the fibroblast-driven collagen and elastin production that follows any controlled skin injury. The treatment is effective for brightening skin tone, softening fine lines, reducing acne scarring, improving texture uniformity, and boosting hydration. A numbing cream is applied before every session. The exosome add-on enhances healing and amplifies collagen output; both are physician-administered for precision depth control.
About this treatment
Microneedling — also called collagen induction therapy (CIT) — works by creating an array of microscopic injury channels in the skin, each barely wider than a hair. These micro-injuries trigger a cascade of events that mirrors the body's natural tissue repair: within minutes, platelets accumulate and begin releasing growth factors; within hours, fibroblasts migrate toward the injury zones; over the following weeks and months, type I and type III collagen…
The Dermapen device at MarBelle Clinic uses a motorised needle cartridge that oscillates vertically at high speed, producing controlled penetration depths that the physician adjusts depending on the zone and concern being treated: shallower settings (0.25–0.5mm) for superficial brightening and skinbooster-effect enhancement; deeper settings (1.0–2.0mm) for established acne scars and significant texture issues; and intermediate depths for overall skin…
The controlled micro-channels also serve as temporary pathways for topical active ingredient delivery — immediately after needling, the skin's permeability increases dramatically. At MarBelle, the exosome add-on exploits this window: extracellular vesicles derived from mesenchymal stem cells are applied to the needled skin immediately post-treatment. These vesicles carry concentrated growth factor payload (EGF, TGF-β, FGF, PDGF) and mRNA molecules that…
Good to know
- Device
- Dermapen (motorised, adjustable depth)
- Standard price
- 2,500 Kč
- With exosomes
- 3,500 Kč
- Healing time
- 1–2 days
- Course
- 5–7 sessions, 2–4 week intervals
Who is this for?
Skin brightening, fine lines, acne scarring, texture irregularities, tone unification, hydration boost
Preparation required
Avoid retinoids and AHAs 48 hours before. Do not have active breakouts across the treatment area. Arrive makeup-free. Avoid sunburn in the week before treatment.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
The clinic is led by Prim. MUDr. Martina Matzenauer, founder and CEO, a dermatologist who holds a primary specialisation in dermatovenerology and has developed the clinic's philosophy of psychodermatology integration — treating the connection between skin health and patient wellbeing. Plastic surgery is performed by MUDr. Pavel Xinopulos and MUDr. Richard Billich, Ph.D., both certified plastic surgeons. The clinical…
Languages: cs, en
Treatment highlights
- Numbing cream application (30–45 min prior)
- Physician-performed Dermapen microneedling session
+1 more item in What's included
Standard microneedling (face): 2,500 Kč. Microneedling + exosomes (face or scar focus): 3,500 Kč. Numbing cream included in both options. No additional fees.

