Type
Botox & Fillers
Duration
45 min
What's included
3 deliverables in this treatment
- Numbing cream application (30 min prior)
- Physician-performed injection lipolysis across target area
- Post-treatment observation and aftercare instructions
Injection lipolysis at MarBelle Clinic uses a phosphatidylcholine or deoxycholic acid formulation — injected directly into localised fat deposits — to permanently dissolve a portion of fat cells in the treatment area. The active compound disrupts the fat cell membrane, causing the lipid content to be released and metabolised over the following eight weeks. The most common treatment areas are the submental region (double chin), jowl fat pads, and small body areas including the abdomen, inner arms, and thighs. Two to three sessions spaced eight weeks apart are typically needed.
About this treatment
Injection lipolysis occupies a useful niche in aesthetic medicine between non-invasive fat-reduction technologies and surgical liposuction. For small, well-defined areas of localised fat that do not respond to diet and exercise, targeted injection of lipolytic agents offers a permanent reduction in fat cell number without surgery, general anaesthesia, or significant downtime.
The mechanism involves injection of a compound — at MarBelle, this is likely a phosphatidylcholine/deoxycholic acid (PC/DC) formulation or a deoxycholic acid (ATX-101 class) product — into the hypodermis (subcutaneous fat layer). Deoxycholic acid is a bile acid that occurs naturally in the body and functions as a detergent — it disrupts phospholipid bilayer membranes. When injected into adipose tissue, it selectively lyses the lipid-bilayer membrane of…
The destroyed fat cells do not regenerate — the result is a permanent reduction in the number of adipocytes in the treated area, providing durable reduction of the treated fat deposit as long as the patient does not gain significant weight (which expands existing fat cells rather than creating new ones in the treated zone).
Good to know
- Mechanism
- Permanent fat cell lysis via deoxycholic acid
- Common areas
- Double chin, jowls, abdomen, arms, thighs
- Sessions needed
- 2–3 sessions, 8 weeks apart
- Downtime
- 1 week swelling (mechanism of action)
- Result
- Permanent fat reduction
Who is this for?
Localised fat deposits resistant to diet and exercise — submental fullness (double chin), buccal fat, small body areas
Preparation required
Avoid blood thinners 5–7 days before. Do not arrange social commitments for the week after treatment (swelling expected). Arrive with clean skin.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
The clinic is led by Prim. MUDr. Martina Matzenauer, founder and CEO, a dermatologist who holds a primary specialisation in dermatovenerology and has developed the clinic's philosophy of psychodermatology integration — treating the connection between skin health and patient wellbeing. Plastic surgery is performed by MUDr. Pavel Xinopulos and MUDr. Richard Billich, Ph.D., both certified plastic surgeons. The clinical…
Languages: cs, en
Treatment highlights
- Numbing cream application (30 min prior)
- Physician-performed injection lipolysis across target area
+1 more item in What's included
Submental chin area: 3,500 Kč. Jowl area (buccal fat pads): 3,500 Kč. Body areas (abdomen, arms, thighs): 5,000 Kč. 2–3 sessions typically needed, spaced 8 weeks apart.