


Type
Botox & Fillers
Duration
1 hour
What's included
3 deliverables in this treatment
- Physician consultation and area mapping
- Dysport injection grid treatment across target area
- Topical numbing (applied for palm/sole treatments)
For patients experiencing problematic excessive sweating — hyperhidrosis — that fails to respond to prescription-strength antiperspirants, botulinum toxin injection offers a well-established, reversible solution. MarBelle Clinic uses Dysport injected in a grid pattern across the affected area to temporarily block the cholinergic nerve signals to eccrine sweat glands, reducing sweat production by 80–90% for six to nine months. Treatment is available for the underarms, palms, and soles of the feet — the three most commonly affected sites in primary focal hyperhidrosis.
About this treatment
Primary focal hyperhidrosis is a condition affecting approximately 2–3% of the population, producing sweating that is disproportionate to thermoregulatory needs. For those affected, it has significant quality-of-life consequences — social anxiety, wardrobe limitations, occupational impact, and skin maceration and infection risks. When topical treatments (including aluminium chloride hexahydrate) fail or cause skin irritation, botulinum toxin injection is…
The mechanism differs from its aesthetic application: rather than blocking the somatic motor nerve signal to skeletal muscle, hyperhidrosis treatment blocks the sympathetic cholinergic innervation of eccrine sweat glands. These glands, which produce watery eccrine sweat in response to temperature and emotional stimuli, become temporarily non-responsive to their nerve signal and stop secreting.
At MarBelle Clinic, the procedure is performed using Dysport — a botulinum toxin A formulation with established data for hyperhidrosis treatment. The injection protocol involves mapping the treatment area and placing injections in a regular grid, typically 1–2 cm apart, to ensure even coverage of the gland field. For underarms, this involves approximately 15–20 injection points per side; for palms and soles, the grid covers the entire glandular zone of…
Good to know
- Product
- Dysport (botulinum toxin A)
- Reduction
- 80–90% sweat reduction
- Duration
- 6–9 months per treatment
- Areas treated
- Underarms, palms, or soles of feet
- Downtime
- None
Who is this for?
Primary focal hyperhidrosis not controlled by topical antiperspirants — underarms, palms, or soles
Preparation required
Avoid shaving the treatment area 48 hours before underarm treatment. Do not apply antiperspirant on the day of treatment. For palm/sole treatment, wear comfortable clothing and plan for 60 minutes.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
The clinic is led by Prim. MUDr. Martina Matzenauer, founder and CEO, a dermatologist who holds a primary specialisation in dermatovenerology and has developed the clinic's philosophy of psychodermatology integration — treating the connection between skin health and patient wellbeing. Plastic surgery is performed by MUDr. Pavel Xinopulos and MUDr. Richard Billich, Ph.D., both certified plastic surgeons. The clinical…
Languages: cs, en
Treatment highlights
- Physician consultation and area mapping
- Dysport injection grid treatment across target area
+1 more item in What's included
Underarms (both sides): 12,000 Kč. Palms: 14,000 Kč. Soles of feet: 14,000 Kč. Each price covers a single treatment session for the stated body area. Effect typically lasts 6–9 months.

