Type
Microneedling
Duration
45 min
What's included
3 deliverables in this treatment
- Physician consultation and skin assessment for polynucleotide biostimulation
- Rejuran (salmon PDRN) injection into the target skin areas
- Post-treatment care instructions and course scheduling
Rejuran polynucleotide treatment at L centrum Pardubice uses salmon-derived PDRN (polydeoxyribonucleotide) — a biological extract that stimulates the skin's own repair and regeneration pathways from within. When injected into the dermis, the polynucleotide fragments act as biological growth factor stimulants, activating fibroblasts to produce new collagen, improving skin elasticity and reducing the appearance of fine lines and pores. Unlike fillers that add volume mechanically, Rejuran works by triggering the skin's biological repair response, resulting in healthier, thicker skin over a course of treatment. The product is widely used in South Korea and gaining clinical adoption across Europe for its documented skin quality improvement effect.
About this treatment
Rejuran (PDRN — polydeoxyribonucleotide) biostimulation at L centrum Pardubice represents the clinic's offering in the category of injectable biological tissue repair agents, distinct from hyaluronic acid fillers (which add volume) and botulinum toxin (which reduces muscle activity). PDRN is a purified extract of salmon sperm DNA that has undergone extensive fragmentation and sterilisation; the resulting polynucleotide chains are structurally compatible…
Good to know
- Product
- Rejuran — salmon-derived PDRN polynucleotides
- Mechanism
- A2A receptor agonism — fibroblast activation + anti-inflammatory
- Effect
- Improved skin thickness, elasticity, pores, fine lines
- vs fillers
- Biological repair vs mechanical volume — different mechanism
Who is this for?
Adults with skin dullness, enlarged pores, reduced elasticity or fine lines who want biological skin quality improvement through PDRN biostimulation rather than volume addition from fillers.
Preparation required
Book a physician consultation. Avoid blood-thinning medications for 3–5 days before. Arrive with clean skin. Mild redness and micro-papules at injection sites are expected and resolve within 1–3 days. Plan a maintenance session every 6–12 months after the initial course.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
L centrum Pardubice is led by MUDr. Drahomíra Kotlářová, founder and lead physician, who has directed the clinic for over 25 years. MUDr. Kotlářová combines a background in medicine with a philosophy she describes as artistic precision — tailoring each aesthetic procedure to the individual patient's facial anatomy and goals. The clinic website describes her as both physician and artist. All aesthetic treatments at…
Clinic-reported credentials
Languages: Czech
Treatment highlights
- Physician consultation and skin assessment for polynucleotide biostimulation
- Rejuran (salmon PDRN) injection into the target skin areas
+1 more item in What's included
From 5,000 Kč per session. Includes physician consultation and injectable polynucleotide (PDRN) biostimulation session. Price confirmed at consultation depending on areas treated and number of sessions planned. Rejuran (salmon-derived PDRN) is used as the injectable biostimulant.