Magnesium + Vitamin B6 Injection

Magnesium and vitamin B6 (pyridoxine) work synergistically — magnesium supports hundreds of enzymatic processes including muscle relaxation, nerve conduction, and energy metabolism, while B6 enhances magnesium's cellular uptake and is a co-factor in neurotransmitter synthesis. IVC Olomouc offers this combined intramuscular injection at 150 Kč per dose. It is commonly used for muscle cramps, tension, stress-related symptoms, and PMS (premenstrual syndrome), where both magnesium and B6 have established roles. The injection bypasses the digestive absorption limits that reduce the effectiveness of oral magnesium in many people.

Magnesium is the fourth most abundant mineral in the human body and the second most abundant intracellular cation after potassium. It acts as a cofactor in over 300 enzymatic reactions, including ATP synthesis, DNA repair, protein biosynthesis, and — critically for this application — muscle contraction and relaxation. Magnesium works antagonistically to calcium at the muscle cell level: calcium triggers contraction, and magnesium promotes relaxation. Low magnesium is associated with muscle cramping, hyperirritability of the nervous system, poor sleep, anxiety, and cardiovascular arrhythmias. Vitamin B6 (pyridoxine) enhances magnesium transport into cells and is independently important as a cofactor in the synthesis of serotonin, dopamine, GABA, and other neurotransmitters — explaining its role in mood, stress resilience, and PMS symptom management. The combination of magnesium and B6 has been studied specifically for PMS, with randomised trials showing significant reductions in PMS symptoms including mood changes, water retention, and cramping when both are supplemented together. Oral magnesium is poorly absorbed in many forms and can cause diarrhoea at therapeutic doses; the intramuscular injection at IVC Olomouc delivers the dose directly into muscle tissue for gradual, well-tolerated systemic absorption over hours. The injection is brief — approximately five to ten minutes — and requires no IV line. It is suitable for patients with muscle cramps associated with exercise, electrolyte imbalance, or pregnancy, those experiencing stress-related tension and sleep difficulties, women managing PMS symptoms, and anyone who has found oral magnesium supplementation insufficient or poorly tolerated. At 150 Kč, it is one of the most accessible entries on the clinic's menu.