NAD+ 250mg IV Drip

An intravenous infusion delivering 250mg of nicotinamide adenine dinucleotide (NAD+), a coenzyme central to cellular energy metabolism, DNA repair, and the regulation of ageing-related pathways. NAD+ levels decline naturally with age, and supplementation is an area of active longevity research.

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in every living cell, serving as an essential electron carrier in the metabolic reactions that convert food into cellular energy. Beyond its role in energy metabolism, NAD+ is a required substrate for sirtuins — a family of enzymes implicated in DNA repair, gene expression regulation, and cellular stress responses — and for poly(ADP-ribose) polymerases (PARPs), which are critical for maintaining genomic integrity. Research has consistently demonstrated that NAD+ levels decline with age, and this decline has been associated in preclinical studies with various hallmarks of ageing including mitochondrial dysfunction, impaired DNA repair capacity, and reduced cellular resilience. Whether restoring NAD+ levels through supplementation can meaningfully influence human ageing trajectories remains an active and evolving area of investigation, with clinical trials ongoing across multiple institutions worldwide. Intravenous NAD+ delivery bypasses the digestive system entirely, achieving plasma levels that oral supplementation cannot readily replicate. The 250mg dose offered at IV Drip Milano is a standard clinical dose used across IV therapy providers internationally. The infusion is typically administered over a longer duration than standard nutrient drips to minimise the transient flushing sensation that NAD+ can produce. All sessions are conducted by ICU/ER-experienced registered nurses in a clinical environment.