Vitamin D, B12, and Iron - ThyroidChange
Type
Blood Testing
Biomarkers
9
Duration
30 min
Results
48 hours
Comprehensive blood test analyzing Vitamin D, B12, and Iron levels relevant to thyroid health.
A thyroid panel evaluates how well your thyroid gland is functioning by measuring the hormones it produces and the pituitary signal that controls it. The thyroid is a butterfly-shaped gland in your neck that regulates metabolism, energy, body temperature, heart rate, and mood. A basic panel measures TSH (the brain's signal to the thyroid) and Free T4 (the main thyroid hormone). Comprehensive panels add Free T3 (the active hormone), reverse T3, and thyroid antibodies (TPOAb, TGAb) that can detect autoimmune conditions like Hashimoto's thyroiditis or Graves' disease. Thyroid dysfunction is extremely common — affecting roughly 1 in 8 women — and often goes undiagnosed because symptoms mimic stress, aging, or depression.
Key Details
Who Is This For?
Anyone experiencing unexplained fatigue, weight changes, hair loss, cold sensitivity, or mood disturbances. People with a family history of thyroid disease or autoimmune conditions. Women planning pregnancy, as thyroid function is critical for fetal brain development. Anyone who has had a 'normal' TSH result but still suspects thyroid dysfunction.
What's Included
Preparation Required
No fasting required for a standalone thyroid panel. If you take thyroid medication (levothyroxine/Synthroid), take your dose after the blood draw, not before — taking it beforehand can temporarily spike T4 levels and skew results. Morning testing is recommended for the most consistent TSH readings, as TSH follows a circadian rhythm and peaks overnight.
Biomarkers Tested
9Active vitamin B12 is the biologically active form of vitamin B12 that is essential for many physiological processes in the body, including the production of red blood cells, DNA synthesis, and nerve function.
The best indicator of overall vitamin D status. Vitamin D is essential for calcium absorption, bone health, immune function, and mood regulation. Deficiency is extremely common, especially in northern latitudes, and linked to increased disease risk.
A mineral essential for oxygen transport (in hemoglobin), energy production, and immune function. Serum iron measures the amount circulating in blood, but ferritin and TIBC provide a more complete picture of iron status.
Transferrin is a protein that binds and transports iron in the blood. Abnormal levels can indicate iron metabolism disorders.
The percentage of transferrin (iron-transporting protein) that is carrying iron. Calculated from serum iron and TIBC. Low saturation indicates iron deficiency; high saturation may indicate hemochromatosis (iron overload).
The primary iron storage protein. Ferritin reflects total body iron stores and is the first marker to drop in iron deficiency. However, ferritin also rises with inflammation, infection, and liver disease, which can mask true iron deficiency.
The primary screening test for thyroid function. TSH is produced by the pituitary gland to regulate thyroid hormone production. High TSH indicates an underactive thyroid (hypothyroidism), while low TSH suggests an overactive thyroid (hyperthyroidism).
The unbound, active form of the main thyroid hormone T4. Free T4 directly reflects thyroid gland output and is used alongside TSH to diagnose and monitor thyroid disorders.
The active form of thyroid hormone responsible for regulating metabolism, energy, and body temperature. Free T3 is converted from T4 in tissues and is three to four times more potent than T4.
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- Category
- Diagnostic
- Sample Type
- Blood draw
- Duration
- 30 min
- Results
- 48 hours
i-Screen
i-Screen is an Australian health service offering blood testing and analytics to help individuals understand and monitor their health through personalized online dashboards.