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Male Sex Hormone Panel - ThyroidChange

Type

Blood Testing

Biomarkers

11

Duration

30 min

Results

48 hours

Hormone blood test measuring key hormones and androgens governing masculinity and fertility.

A thyroid panel evaluates how well your thyroid gland is functioning by measuring the hormones it produces and the pituitary signal that controls it. The thyroid is a butterfly-shaped gland in your neck that regulates metabolism, energy, body temperature, heart rate, and mood. A basic panel measures TSH (the brain's signal to the thyroid) and Free T4 (the main thyroid hormone). Comprehensive panels add Free T3 (the active hormone), reverse T3, and thyroid antibodies (TPOAb, TGAb) that can detect autoimmune conditions like Hashimoto's thyroiditis or Graves' disease. Thyroid dysfunction is extremely common — affecting roughly 1 in 8 women — and often goes undiagnosed because symptoms mimic stress, aging, or depression.

Key Details

Biomarkers
2–7 thyroid markers
Fasting Required
No
Sample Type
Blood draw
Turnaround
24–48 hours
Common Use
Thyroid function, autoimmune screening

Who Is This For?

Anyone experiencing unexplained fatigue, weight changes, hair loss, cold sensitivity, or mood disturbances. People with a family history of thyroid disease or autoimmune conditions. Women planning pregnancy, as thyroid function is critical for fetal brain development. Anyone who has had a 'normal' TSH result but still suspects thyroid dysfunction.

What's Included

Thyroid-stimulating hormone (TSH)
Free Thyroxine (FT4)
Free Triiodothyronine (FT3) — if comprehensive panel
Thyroid antibodies (TPOAb, TGAb) — if autoimmune panel

Preparation Required

No fasting required for a standalone thyroid panel. If you take thyroid medication (levothyroxine/Synthroid), take your dose after the blood draw, not before — taking it beforehand can temporarily spike T4 levels and skew results. Morning testing is recommended for the most consistent TSH readings, as TSH follows a circadian rhythm and peaks overnight.

Biomarkers Tested

11
Testosterone (Total) ng/dL

The primary male sex hormone, also important in women at lower levels. Testosterone regulates muscle mass, bone density, fat distribution, libido, and mood. Levels decline naturally with age in both sexes.

Free Testosterone pg/mL

The unbound, biologically active fraction of testosterone (typically 1–3% of total). Free testosterone is the form that can enter cells and exert effects. More clinically relevant than total testosterone for assessing hormonal status.

SHBG (Sex Hormone-Binding Globulin) nmol/L

A protein that binds and transports sex hormones (testosterone, estrogen) in the blood. High SHBG reduces the amount of free, active hormones available. SHBG increases with age, thyroid hormones, and estrogen; decreases with obesity and insulin resistance.

Estradiol (E2) pg/mL

The most potent and prevalent form of estrogen. In women, estradiol regulates the menstrual cycle, fertility, and bone density. In men, it's produced from testosterone and plays roles in bone health and libido. Levels vary significantly with age and menstrual cycle.

Follicle-Stimulating Hormone (FSH) mIU/mL

Stimulates egg maturation; high levels indicate poor ovarian reserves.

LH (Luteinizing Hormone) mIU/mL

Works with FSH to regulate reproductive function. In women, an LH surge triggers ovulation. In men, LH stimulates testosterone production. Abnormal levels can indicate pituitary or gonadal disorders.

Progesterone ng/mL

A hormone essential for menstrual cycle regulation and pregnancy maintenance. Progesterone rises after ovulation, preparing the uterus for implantation. Low levels can cause irregular periods and difficulty maintaining pregnancy.

Prolactin ng/mL

A hormone primarily known for stimulating breast milk production. Elevated prolactin in non-pregnant individuals can indicate pituitary tumors, medication side effects, or hypothyroidism. High levels can suppress reproductive hormones.

TSH (Thyroid-Stimulating Hormone) mIU/L

The primary screening test for thyroid function. TSH is produced by the pituitary gland to regulate thyroid hormone production. High TSH indicates an underactive thyroid (hypothyroidism), while low TSH suggests an overactive thyroid (hyperthyroidism).

Free T4 (Thyroxine) ng/dL

The unbound, active form of the main thyroid hormone T4. Free T4 directly reflects thyroid gland output and is used alongside TSH to diagnose and monitor thyroid disorders.

Free T3 (Triiodothyronine) pg/mL

The active form of thyroid hormone responsible for regulating metabolism, energy, and body temperature. Free T3 is converted from T4 in tissues and is three to four times more potent than T4.

Frequently Asked Questions