i-Screen Coeliac HLA Typing
Type
Blood Testing
Biomarkers
6
Duration
30 min
Results
4 days
Genetic test to identify HLA-DQ2 and HLA-DQ8 alleles associated with coeliac disease risk.
Celiac disease blood testing screens for antibodies that indicate an autoimmune reaction to gluten — a protein found in wheat, barley, and rye. The primary marker is tissue transglutaminase IgA (tTG-IgA), which is positive in roughly 98% of people with active celiac disease. Total IgA is also measured because some people have IgA deficiency, which can cause false-negative celiac results. Celiac disease affects approximately 1% of the population globally but is significantly underdiagnosed, with most cases going undetected for years. Left untreated, celiac disease can lead to nutrient malabsorption, osteoporosis, infertility, and increased risk of certain cancers.
Key Details
- Biomarkers
- 2–4 celiac markers
- Fasting Required
- No
- Key Requirement
- Must be eating gluten for accurate results
- Sample Type
- Blood draw
- Turnaround
- 3–5 business days
Who Is This For?
Anyone experiencing chronic digestive symptoms like bloating, diarrhea, or abdominal pain. People with unexplained iron deficiency anemia, fatigue, or bone loss. Those with a family history of celiac disease (10% risk in first-degree relatives). Anyone considering going gluten-free who wants a diagnosis first — important because testing is only accurate while eating gluten.
What's Included
Preparation Required
You must be eating gluten regularly for at least 6 weeks before testing — eliminating gluten before the test can cause a false negative. No fasting required. Continue your normal diet including bread, pasta, and other gluten-containing foods.
Biomarkers Tested
6One of the primary genetic factors associated with coeliac disease.
One of the primary genetic factors associated with coeliac disease.
HLA-DQ2 allele associated with coeliac disease.
HLA-DQ2 allele associated with coeliac disease.
HLA-DQ8 allele associated with coeliac disease.
HLA-DQ8 allele associated with coeliac disease.
- Category
- Diagnostic
- Sample Type
- Blood draw
- Duration
- 30 min
- Results
- 4 days