i-Screen Advanced Thyroid Check
Type
Blood Testing
Biomarkers
5
Duration
30 min
Results
3 days
Comprehensive thyroid function and antibodies test to assess thyroid health and detect autoimmune disorders.
The i-Screen Advanced Thyroid Check provides a thorough assessment of thyroid function and screens for autoimmune thyroid disease. It measures the three key thyroid hormones — TSH, Free T4, and Free T3 — along with thyroid antibodies (TPOAb and TGAb) that can indicate autoimmune conditions like Hashimoto's thyroiditis or Graves' disease. Thyroid hormones regulate metabolism, energy levels, body temperature, and mood. When antibodies attack the thyroid, they can cause chronic inflammation and disrupt hormone production — leading to symptoms that are often mistaken for stress, aging, or depression. This panel is more comprehensive than the basic thyroid screen most GPs order, which typically only includes TSH.
Key Details
Who Is This For?
Anyone experiencing unexplained fatigue, weight changes, hair loss, or mood changes. People with a family history of thyroid disease or autoimmune conditions. Women planning pregnancy (thyroid function is critical for fetal development). Anyone who has had a 'normal' TSH result but still suspects thyroid dysfunction — the antibody markers in this panel can reveal autoimmune activity that TSH alone misses.
What's Included
Preparation Required
No fasting required for this blood test. Continue taking regular medications as prescribed. If you are taking thyroid medication (levothyroxine), take your dose after the blood draw, not before. Morning testing is recommended for the most consistent TSH readings. The blood draw takes approximately 5 minutes at an i-Screen partner collection center. Results are typically available within 3 business days via the i-Screen online dashboard.
Biomarkers Tested
5The primary screening test for thyroid function. TSH is produced by the pituitary gland to regulate thyroid hormone production. High TSH indicates an underactive thyroid (hypothyroidism), while low TSH suggests an overactive thyroid (hyperthyroidism).
The unbound, active form of the main thyroid hormone T4. Free T4 directly reflects thyroid gland output and is used alongside TSH to diagnose and monitor thyroid disorders.
The active form of thyroid hormone responsible for regulating metabolism, energy, and body temperature. Free T3 is converted from T4 in tissues and is three to four times more potent than T4.
Antibodies against thyroid peroxidase, an enzyme essential for thyroid hormone production. Positive TPO antibodies indicate autoimmune thyroid disease, most commonly Hashimoto's thyroiditis, even before symptoms or TSH changes appear.
Antibodies against thyroglobulin, a protein used by the thyroid to produce hormones. Elevated TGAb, along with TPO antibodies, confirms autoimmune thyroid disease. Also monitored after thyroid cancer treatment.
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- Category
- Diagnostic
- Sample Type
- Blood draw
- Duration
- 30 min
- Results
- 3 days
i-Screen
i-Screen is an Australian health service offering blood testing and analytics to help individuals understand and monitor their health through personalized online dashboards.
