i-Screen Advanced DUTCH Check
Type
Blood Testing
Biomarkers
56
Duration
30 min
Results
14 days
Comprehensive hormone analysis using dried urine to assess hormone balance and identify potential imbalances.
Adrenal and stress hormone profiling tests — including the DUTCH (Dried Urine Test for Comprehensive Hormones) — provide a detailed picture of how your body produces, metabolizes, and eliminates stress hormones and sex hormones throughout the day. Unlike a single blood draw that captures one moment in time, these tests typically collect multiple samples over 24 hours to map your cortisol curve — the natural rise and fall of cortisol that should peak in the morning and decline through the day. The DUTCH test goes further by measuring hormone metabolites, revealing how your body processes hormones through specific enzymatic pathways. This information is invaluable for functional medicine practitioners investigating chronic fatigue, sleep issues, weight resistance, and hormonal imbalances.
Key Details
Who Is This For?
People with chronic fatigue, burnout, or suspected adrenal dysfunction. Those with sleep issues — particularly difficulty waking or evening energy spikes. Women with hormonal imbalances including PCOS, endometriosis, or difficult perimenopause. Anyone working with a functional medicine practitioner who wants detailed hormone metabolism data.
What's Included
Preparation Required
Follow the specific collection instructions included with your test kit. Most adrenal profiles require multiple samples throughout the day (morning, afternoon, evening, night). DUTCH tests use dried urine on filter paper. Saliva cortisol tests require timed samples. Avoid eating, drinking (other than water), or brushing teeth 30 minutes before saliva collection.
Biomarkers Tested
56The most potent and prevalent form of estrogen. In women, estradiol regulates the menstrual cycle, fertility, and bone density. In men, it's produced from testosterone and plays roles in bone health and libido. Levels vary significantly with age and menstrual cycle.
Oestrogen produced in ovaries and other tissues; levels change with age and menopause.
Weakest oestrogen, produced in the placenta during pregnancy; has oestrogenic and anti-oestrogenic effects.
Calculation of Oestriol/(Oestradiol + Oestrone).
Metabolite of estradiol.
Metabolite of estrone.
Metabolite of estradiol.
Metabolite of estrone.
Metabolite of estrone.
Ratio of estrogen metabolites.
Metabolite of estradiol.
Metabolite of estrone.
Ratio of estrogen metabolites.
Metabolite of estradiol.
Metabolite of estrone.
Ratio of estrogen metabolites.
Ratio of estrogen metabolites.
Metabolite of progesterone.
Neuroactive steroid metabolite of progesterone.
Metabolite of progesterone.
Metabolite of progesterone.
Metabolite of progesterone.
A steroid hormone produced by the adrenal glands.
A steroid hormone produced by the adrenal glands.
Ratio of pregnanediol to estradiol.
A hormone produced by the adrenal glands, serving as a precursor to testosterone and estrogen. DHEA peaks in early adulthood and declines steadily with age. It's one of the most studied biomarkers in anti-aging research.
Androstenedione is a steroid hormone and a precursor to testosterone and estrogen. Abnormal levels can indicate adrenal or reproductive disorders.
A metabolite of testosterone.
A metabolite of testosterone.
The primary male sex hormone, also important in women at lower levels. Testosterone regulates muscle mass, bone density, fat distribution, libido, and mood. Levels decline naturally with age in both sexes.
Metabolite of testosterone.
Ratio of testosterone to epitestosterone.
5α-Dihydrotestosterone, a potent androgen.
Metabolite of testosterone.
Total cortisol levels in urine.
Total cortisone levels in urine.
Ratio of cortisol to cortisone.
Metabolite of cortisol.
Metabolite of cortisone.
Free cortisol levels in the first morning urine sample.
Free cortisol levels in the first morning urine sample.
Free cortisol levels in the evening urine sample.
Free cortisol levels in the night urine sample.
Free cortisol levels in the first morning urine sample.
Free cortisol levels in the first morning urine sample.
Free cortisol levels in the evening urine sample.
Free cortisol levels in the night urine sample.
Melatonin levels in the first morning urine sample.
Melatonin levels in the second morning urine sample.
Melatonin levels in the evening urine sample.
Melatonin levels in the night urine sample.
Creatinine levels in the pooled urine sample.
Creatinine levels in the first morning urine sample.
Creatinine levels in the second morning urine sample.
Creatinine levels in the evening urine sample.
Creatinine levels in the night urine sample.
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- Category
- Diagnostic
- Sample Type
- Dried urine or saliva (varies by test)
- Duration
- 30 min
- Results
- 14 days
i-Screen
i-Screen is an Australian health service offering blood testing and analytics to help individuals understand and monitor their health through personalized online dashboards.
