HIV Ag/Ab Combo (with P24 Antigen)

4th-generation HIV screening test detecting both HIV 1/2 antibodies and p24 antigen simultaneously. The dual-detection approach narrows the diagnostic window compared to older antibody-only assays, providing reliable results from approximately 4-6 weeks after potential exposure. At 45 PLN (~10.40 EUR) plus collection fee.

The 4th-generation HIV combination test represents the current standard of care for HIV screening. By simultaneously detecting HIV 1/2 antibodies and the p24 capsid antigen, it identifies infection earlier than antibody-only assays. The p24 antigen appears in blood approximately 2-3 weeks after infection, during the acute viraemic phase, before the adaptive immune system generates detectable antibodies at 3-6 weeks. This dual approach narrows the diagnostic window period to approximately 4 weeks for most individuals, compared to 6-12 weeks for 3rd-generation antibody-only tests. A negative result at 6 weeks post-exposure is considered conclusive by European Centre for Disease Prevention and Control guidelines. The test is performed on a standard venous blood sample and requires no fasting or special preparation. A reactive screening result is always followed by confirmatory testing — typically a Western blot or immunoblot — before a definitive diagnosis is made. InterLab can arrange confirmatory testing if the screening result is reactive. Poland has a relatively low HIV prevalence (estimated 0.1% of the adult population), but late diagnosis remains a significant public health challenge — approximately 50% of new HIV diagnoses in Poland are made at an advanced stage of infection. Routine screening, particularly after potential exposure events, supports early detection and treatment initiation. For comprehensive STI screening, consider combining this test with hepatitis B surface antigen (HBsAg), hepatitis C antibodies (anti-HCV), and syphilis serology, all available at InterLab at competitive prices.