PRP — Platelet-Rich Plasma Therapy

Infinity Clinic administers autologous platelet-rich plasma (PRP) injections for orthopaedic and musculoskeletal conditions, under the supervision of the clinic's trauma-orthopaedic team. PRP is prepared from the patient's own blood — a small sample is drawn, centrifuged to concentrate platelets and growth factors, then injected into the affected joint, tendon, or soft tissue. The growth factor concentration in PRP may support tissue repair, reduce inflammation, and accelerate healing in conditions such as osteoarthritis, tendinopathy, and joint degeneration. The procedure takes approximately 45 minutes in total and is performed under sterile technique. At 3,000–9,000 Kč depending on dosage, this offers a biologic therapy option at a fraction of Western European pricing.

Platelet-Rich Plasma (PRP) therapy at Infinity Clinic — listed in the price list as aplikace separované plazmy (application of separated plasma) — is an autologous biologic treatment used within the orthopaedic and rehabilitation programme. Autologous means the therapy uses the patient's own biological material, eliminating risk of rejection or disease transmission. **The science behind PRP:** Whole blood contains a small percentage of platelets — cell fragments that are central to the clotting cascade and tissue repair. When a blood sample is centrifuged, the platelets are concentrated 3–8 times above baseline into the PRP fraction. This concentrate is rich in alpha-granules containing growth factors including Platelet-Derived Growth Factor (PDGF), Transforming Growth Factor-beta (TGF-β), Vascular Endothelial Growth Factor (VEGF), Insulin-like Growth Factor (IGF-1), and Epidermal Growth Factor (EGF). When injected into damaged tissue, these factors signal local stem cells and fibroblasts to proliferate and deposit new collagen matrix. **Clinical applications at Infinity Clinic:** - Knee osteoarthritis (intra-articular injection to support cartilage and synovial membrane) - Chronic tendinopathy (Achilles, patella, rotator cuff, lateral epicondyle) - Partial tendon and ligament tears where surgery is not immediately indicated - Post-surgical soft tissue augmentation - Adjunct to shock wave therapy for persistent enthesopathy **Procedure protocol:** A 10–30 ml blood draw is performed from the cubital vein. The sample is centrifuged at the clinic to produce the PRP concentrate. Under sterile conditions and often ultrasound-guided (using the clinic's MSK ultrasound capability), the PRP is injected into the target tissue. The patient rests for 15–20 minutes post-injection. Mild swelling and pain at the injection site are expected for 3–5 days — an inflammatory response that is part of the healing mechanism. Activity modification (reduced load on the joint or tendon) is recommended for 2–4 weeks. **Dosing:** Standard single-joint or single-tendon injection is 3,000 Kč. Larger joint volumes or multi-site treatment may require up to three doses at 9,000 Kč. Most evidence supports 1–3 injection courses spaced 4–6 weeks apart for optimal response. The clinic prices each dose at 3,000 Kč and does not mandate a specific course, allowing the supervising physician to adapt the protocol to clinical response.