Botulinum Toxin — Anti-Wrinkle Injections

Infinity Clinic's aesthetic medicine service, led by MUDr. Petra Meluzinová, Ph.D., offers botulinum toxin (Botox) injections for dynamic facial wrinkle relaxation. Treatment areas include forehead horizontal lines, frown lines between the brows (glabella), crow's feet around the eyes, bunny lines at the nose root, and chin dimpling. Botulinum toxin temporarily blocks the neuromuscular signal that causes repeated muscle contractions — the underlying cause of expression lines. Results typically onset within 5–7 days and last 3–5 months. The procedure involves multiple micro-injections delivered in a brief 15–20 minute session, with no anaesthesia required. MUDr. Meluzinová brings doctoral-level surgical training and FESSH membership to her aesthetic medicine practice, offering both precision and safety.

Botulinum toxin type A injections at Infinity Clinic are administered by MUDr. Petra Meluzinová, Ph.D. — a physician whose qualifications extend beyond typical aesthetic medicine training to include a PhD in Surgery, certification in traumatology, and Fellowship of the European Societies for Surgery of the Hand (FESSH). This surgical background means patients benefit from an exceptionally precise understanding of facial anatomy and musculature, reducing the risk of complications associated with less experienced injectors. **Mechanism:** Botulinum toxin is a neuromodulator that binds to the presynaptic membrane of the neuromuscular junction and prevents acetylcholine release. This chemically denervates the targeted muscle, causing temporary paralysis of the hyperdynamic contractions responsible for expression lines. The toxin is irreversible at the molecular level but the neuromuscular junction regenerates over 3–5 months, after which the treatment can be repeated. **Treatment areas covered at the clinic:** - Forehead horizontal lines (frontalis muscle) - Glabellar frown lines — "11 lines" (corrugator supercilii and procerus) - Lateral eye lines — crow's feet (orbicularis oculi, lateral portion) - Bunny lines on nose bridge (nasalis) - Chin dimpling (mentalis muscle) - Lip lines (perioral orbicularis, careful dosing required) - Neck bands (platysma) — neck and lower face rejuvenation - Hyperhidrosis (excessive sweating) in axillae, palms, or soles **Hyperhidrosis treatment:** The clinic explicitly lists treatment of excessive sweating (nadměrné pocení) as an indication for botulinum toxin, which blocks sympathetic sweat gland innervation. This application typically requires higher unit counts than facial aesthetics. **Session experience:** No anaesthesia is required — needle calibre is 31–32G and discomfort is minimal. A topical numbing cream is available for sensitive patients. The face is marked with a skin pen, injections are delivered over 15–20 minutes, and the patient can return to normal activity immediately (avoiding exercise, massage of the area, or lying face-down for 4 hours post-treatment). **Results:** Muscle relaxation begins 3–5 days after injection and is fully evident by day 14. Duration of effect is typically 3–5 months for facial musculature and up to 6–9 months for hyperhidrosis. Dosing is individualised based on muscle mass, facial anatomy, and desired effect — either full relaxation or a softened "natural" look. **Safety:** Contraindications include pregnancy, breastfeeding, active skin infection at the injection site, and known allergy to botulinum toxin products or albumin. The clinic conducts a medical consultation before treatment.