NAD+ Infusion

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, serving as a critical substrate for enzymes involved in energy metabolism (sirtuins), DNA repair (PARPs), and cellular signalling (CD38). Research has established that NAD+ levels decline by approximately 50 percent between age 40 and 60, contributing to mitochondrial dysfunction, impaired DNA repair capacity, and the metabolic changes associated with ageing. Intravenous…

The base NAD+ infusion at IEM SPA delivers NAD+ over a 90-minute session. The extended duration is necessary because NAD+ must be infused slowly to minimise the chest tightness, flushing, and nausea that can occur with rapid administration. Medical staff monitor the drip rate and adjust it to the patient's tolerance, gradually increasing the rate as the body acclimates. Most patients experience only mild warmth or tingling during the infusion.

At 3,000 CZK (approximately 120 EUR), IEM SPA's base NAD+ infusion is priced at a fraction of what clinics in Western Europe charge for equivalent treatments. NAD+ therapy in Berlin typically starts at 250 EUR and in London at 300 to 400 EUR. This pricing makes Prague one of the most accessible destinations in Europe for NAD+ therapy, particularly for patients who want to try it before committing to a multi-session protocol.