NAD+ Infusion

A 90-minute base NAD+ intravenous infusion for cellular repair, mitochondrial function, and longevity support. NAD+ (nicotinamide adenine dinucleotide) is a coenzyme essential for energy metabolism and DNA repair that declines significantly with age.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, serving as a critical substrate for enzymes involved in energy metabolism (sirtuins), DNA repair (PARPs), and cellular signalling (CD38). Research has established that NAD+ levels decline by approximately 50 percent between age 40 and 60, contributing to mitochondrial dysfunction, impaired DNA repair capacity, and the metabolic changes associated with ageing. Intravenous NAD+ supplementation bypasses the multi-step biosynthesis pathway, directly restoring intracellular NAD+ levels. The base NAD+ infusion at IEM SPA delivers NAD+ over a 90-minute session. The extended duration is necessary because NAD+ must be infused slowly to minimise the chest tightness, flushing, and nausea that can occur with rapid administration. Medical staff monitor the drip rate and adjust it to the patient's tolerance, gradually increasing the rate as the body acclimates. Most patients experience only mild warmth or tingling during the infusion. At 3,000 CZK (approximately 120 EUR), IEM SPA's base NAD+ infusion is priced at a fraction of what clinics in Western Europe charge for equivalent treatments. NAD+ therapy in Berlin typically starts at 250 EUR and in London at 300 to 400 EUR. This pricing makes Prague one of the most accessible destinations in Europe for NAD+ therapy, particularly for patients who want to try it before committing to a multi-session protocol. NAD+ therapy is used by longevity-focused patients as part of broader anti-ageing protocols, by athletes for recovery and performance optimisation, and by individuals recovering from chronic fatigue or neurological conditions. A course of three to six infusions spaced one to two weeks apart is commonly recommended for initial restoration, followed by monthly maintenance sessions.