Collagen Biostimulators (Profhilo, Radiesse, Sculptra, Lanluma)

I am clinic carries one of the broadest collagen biostimulator menus in Prague — Profhilo, Radiesse, Sculptra, Ellansé, Lanluma, HarmonyCa, JuveLook, and Gourgi. Unlike conventional fillers that add volume directly, biostimulators trigger your own fibroblasts to produce new collagen over weeks to months, progressively improving skin firmness, density, and quality. Options span bio-remodelling for crepey skin (Profhilo), calcium hydroxyapatite lifting (Radiesse, HarmonyCa), poly-L-lactic acid regeneration (Sculptra, Lanluma — including non-surgical buttock augmentation), and dedicated under-eye treatment (JuveLook).

Collagen biostimulators are the fastest-growing category in aesthetic medicine — products that work *with* your biology rather than simply occupying space. Each product on I am clinic's menu has a distinct mechanism and best-fit indication: **Profhilo (7,000 Kč / 1 area, 12,000 Kč / 2 areas):** An ultra-pure, high-concentration hyaluronic acid 'bio-remodeller' injected at 5 standardised points per side. Rather than filling lines, it spreads through the tissue, deeply hydrating and stimulating collagen and elastin. Best for crepey, dull, laxity-prone skin on the face, neck, or décolletage. Protocol: 2 sessions one month apart. **Radiesse (11,000 Kč; +NCTF 12,000 Kč):** Calcium hydroxyapatite microspheres in a gel — gives an immediate lifting effect followed by months of collagen stimulation. Often used diluted for skin tightening on the face, neck, or hands. The NCTF combination adds a polyrevitalising mesotherapy cocktail. **Sculptra (13,500 Kč / 5 ml, 18,000 Kč / 10 ml) and Lanluma (13,500 Kč):** Poly-L-lactic acid (PLLA) stimulators that rebuild volume gradually over 2–3 months as new collagen forms. Results from a series last up to 2 years. Lanluma is also offered for **non-surgical buttock augmentation and shaping** — 40 ml (25,000 Kč) or 80 ml (50,000 Kč) — one of relatively few Prague clinics publishing prices for PLLA body contouring. **Ellansé (13,500 Kč):** Polycaprolactone-based stimulator combining immediate correction with long-duration collagen renewal (versions lasting 1–2+ years). **HarmonyCa (22,000 Kč):** A hybrid of hyaluronic acid (immediate lift) and calcium hydroxyapatite (lasting collagen stimulation) — the 'dual effect' injectable for midface lifting. **JuveLook (6,000 Kč):** A PDLLA + HA hybrid designed specifically for the delicate under-eye area, improving fine lines and dark-circle texture over a series of sessions. **What to expect:** Results develop progressively — typically visible from 4–6 weeks with peak effect at 3 months. Mild swelling or bruising can occur for a few days. Most protocols involve 1–3 sessions depending on the product and indication; the physician designs the plan at consultation.