Gut Microbiome Testing

Advanced gut microbiome analysis using shotgun metagenomic sequencing to profile bacterial diversity, digestion, nutrient absorption, inflammation, immune function, and metabolic health — with doctor-led consultation and personalised recommendations.

Hisential's gut microbiome testing service uses shotgun metagenomic sequencing — the gold standard in microbiome analysis — to analyse all genetic material in a stool sample and detect bacteria, fungi, and viruses at species and strain level with full functional insights. Unlike standard 16S rRNA panels, shotgun sequencing captures the complete microbial landscape, enabling highly accurate assessment of microbial diversity, functional pathways, and their clinical relevance. The process begins with a simple at-home stool collection kit, followed by laboratory analysis with a 2–3 week turnaround. Results cover bacterial balance and diversity (beneficial vs. pathogenic species), digestion quality (linked to symptoms such as bloating, constipation, or diarrhoea), nutrient absorption capacity, inflammation patterns and immune function status, metabolic and weight management factors, and connections to energy, mood, skin health, and sleep. A doctor then interprets the report and delivers a personalised consultation with actionable guidance on targeted probiotics, dietary modifications, and lifestyle interventions to restore microbiome balance. Gut microbiome testing at Hisential is embedded within its longevity screening packages (included in all four tiers: Janus, Apollo, Helios, and Orion), reflecting the clinic's view that gut health is a foundational pillar of male longevity and performance. It is also available as a standalone assessment for men with specific digestive concerns or those seeking a complete picture of their internal health.