IHHT — Intermittent Hypoxia-Hyperoxia Training

Intermittent hypoxia-hyperoxia training (IHHT) is a mitochondrial conditioning protocol that exposes the body to controlled cycles of reduced oxygen (hypoxia) and elevated oxygen (hyperoxia) through a breathing mask. The alternation mimics aspects of altitude training without physical exertion, triggering a cascade of adaptive responses at the cellular level.

During the hypoxic phase (typically 9-14% oxygen), damaged or inefficient mitochondria are selectively stressed and tagged for recycling through mitophagy — the cell's quality control mechanism for its energy-producing organelles. During the hyperoxic phase (typically 30-40% oxygen), surviving healthy mitochondria receive an abundance of substrate to support biogenesis — the production of new, efficient mitochondria. Over a series of sessions, this cycle…

The treatment at Healthy Horizon runs for 40 minutes at EUR 75 per session, with a 56-minute extended option at EUR 100. Guests recline comfortably while breathing through a mask connected to the IHHT device, which automatically alternates between the hypoxic and hyperoxic phases according to a programmed protocol. IHHT is also included in the Energy Boost day package alongside sauna, cold plunge, red light, and hydrogen therapy.