Functional Health Assessment — 39 Markers

The most abundant mineral in the body, essential for bone health, muscle contraction, nerve function, and blood clotting. Blood calcium is tightly regulated by parathyroid hormone and vitamin D. Abnormal levels can indicate parathyroid disorders.

The primary stress hormone, produced by the adrenal glands. Cortisol regulates metabolism, immune response, blood pressure, and the sleep-wake cycle. Chronically elevated cortisol from stress contributes to weight gain, immune suppression, and metabolic dysfunction.

A waste product from normal muscle metabolism, filtered by the kidneys. Blood creatinine levels reflect kidney filtration capacity. Elevated levels may indicate impaired kidney function, dehydration, or excessive muscle breakdown.

Precursor to other hormones

The most potent and prevalent form of estrogen. In women, estradiol regulates the menstrual cycle, fertility, and bone density. In men, it's produced from testosterone and plays roles in bone health and libido. Levels vary significantly with age and menstrual cycle.

The primary iron storage protein. Ferritin reflects total body iron stores and is the first marker to drop in iron deficiency. However, ferritin also rises with inflammation, infection, and liver disease, which can mask true iron deficiency.

The active form of thyroid hormone responsible for regulating metabolism, energy, and body temperature. Free T3 is converted from T4 in tissues and is three to four times more potent than T4.

The unbound, active form of the main thyroid hormone T4. Free T4 directly reflects thyroid gland output and is used alongside TSH to diagnose and monitor thyroid disorders.

Regulates reproductive function in both sexes. In women, FSH stimulates egg development; elevated levels indicate declining ovarian reserve or menopause. In men, FSH stimulates sperm production.

A liver enzyme sensitive to alcohol use and bile duct problems. GGT is often the first liver enzyme to rise when bile ducts are blocked. Combined with ALP, it helps determine whether elevated ALP is from liver or bone.

Measures blood glucose levels after fasting, indicating how well the body regulates blood sugar.

Reflects your average blood sugar over the past 2–3 months by measuring the percentage of hemoglobin with attached glucose. HbA1c is the gold standard for diagnosing and monitoring diabetes, unaffected by daily fluctuations.

Often called 'good' cholesterol, HDL carries cholesterol away from arteries back to the liver for removal. Higher HDL levels are protective against heart disease. Exercise, healthy fats, and moderate alcohol intake can raise HDL.

An amino acid produced during protein metabolism. Elevated homocysteine is an independent risk factor for cardiovascular disease, stroke, and cognitive decline. Levels are lowered by adequate B12, folate, and B6 intake.

A highly sensitive test for low-grade chronic inflammation linked to cardiovascular disease risk. Lower hs-CRP values are associated with better cardiovascular outcomes.

A hormone produced mainly by the liver in response to growth hormone. IGF-1 mediates many of growth hormone's effects on tissue growth and repair. It's more stable than GH, making it a better marker for growth hormone status.

The hormone produced by the pancreas to regulate blood sugar. Elevated fasting insulin — even with normal glucose — is an early marker of insulin resistance, which precedes type 2 diabetes by years. Key biomarker in longevity medicine.

A mineral essential for oxygen transport (in hemoglobin), energy production, and immune function. Serum iron measures the amount circulating in blood, but ferritin and TIBC provide a more complete picture of iron status.

Often called 'bad' cholesterol, LDL deposits cholesterol in artery walls, contributing to plaque buildup and atherosclerosis. LDL is the primary target for cardiovascular risk reduction through diet, exercise, and medication.

Works with FSH to regulate reproductive function. In women, an LH surge triggers ovulation. In men, LH stimulates testosterone production. Abnormal levels can indicate pituitary or gonadal disorders.

Involved in over 300 enzymatic reactions including energy production, muscle function, and nerve signaling. Magnesium deficiency is common and associated with muscle cramps, anxiety, insomnia, and increased cardiovascular risk.

A hormone primarily known for stimulating breast milk production. Elevated prolactin in non-pregnant individuals can indicate pituitary tumors, medication side effects, or hypothyroidism. High levels can suppress reproductive hormones.

Protein binding testosterone and oestradiol; changes affect hormone availability.

The primary male sex hormone, also important in women at lower levels. Testosterone regulates muscle mass, bone density, fat distribution, libido, and mood. Levels decline naturally with age in both sexes.

Antibodies against thyroglobulin, a protein used by the thyroid to produce hormones. Elevated TGAb, along with TPO antibodies, confirms autoimmune thyroid disease. Also monitored after thyroid cancer treatment.

The combined measure of all cholesterol in your blood, including HDL, LDL, and VLDL. While useful as an overview, the breakdown between HDL and LDL is more clinically meaningful for assessing cardiovascular risk.

The most common type of fat in the body, stored for energy. Elevated triglycerides — often from excess sugar, alcohol, or calories — increase cardiovascular risk and can cause pancreatitis at very high levels.

The primary screening test for thyroid function. TSH is produced by the pituitary gland to regulate thyroid hormone production. High TSH indicates an underactive thyroid (hypothyroidism), while low TSH suggests an overactive thyroid (hyperthyroidism).

A waste product from protein breakdown, processed by the liver and excreted by the kidneys. Elevated urea levels can indicate kidney dysfunction, dehydration, high-protein diet, or gastrointestinal bleeding.

Essential for nerve function, DNA synthesis, and red blood cell formation. B12 deficiency can cause anemia, neuropathy, fatigue, and cognitive impairment. Common in vegans, vegetarians, older adults, and those taking metformin or acid-reducing medications.

The best indicator of overall vitamin D status. Vitamin D is essential for calcium absorption, bone health, immune function, and mood regulation. Deficiency is extremely common, especially in northern latitudes, and linked to increased disease risk.