NAD+ Infusion

A 120-minute full-dose NAD+ (nicotinamide adenine dinucleotide) intravenous infusion for cellular repair, mitochondrial function, DNA maintenance, and longevity support.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, essential for over 500 enzymatic reactions including mitochondrial energy production, DNA repair (via PARP enzymes), epigenetic regulation (via sirtuin activation), and cellular stress response. NAD+ levels decline approximately 50% between ages 40 and 60, and this decline is now considered a hallmark of ageing — directly contributing to mitochondrial dysfunction, genomic instability, and impaired cellular repair capacity. IV NAD+ delivery is the most direct method of raising intracellular NAD+ levels. Unlike oral precursors (NMN, NR) which require multi-step enzymatic conversion and compete with gut bacteria for absorption, IV NAD+ enters the bloodstream as the active molecule. The 120-minute infusion time reflects the slow drip rate required for NAD+ — rapid infusion causes uncomfortable flushing, chest tightness, and nausea due to the molecule's interaction with purinergic receptors. Experienced IV clinics like heal. manage the drip rate carefully to maintain patient comfort. The longevity research around NAD+ is substantial: sirtuin enzymes (SIRT1-7), which regulate DNA repair, inflammation, and mitochondrial biogenesis, are entirely dependent on NAD+ as a substrate. PARP enzymes, the primary DNA repair machinery, also consume NAD+ with each repair cycle — meaning that accumulated DNA damage from ageing and environmental exposure progressively depletes the very molecule needed to fix it, creating a vicious cycle that IV NAD+ can interrupt. At €249, the NAD+ Infusion is heal.'s premium longevity treatment. The 2-hour session is typically recommended as a series of 3-4 infusions over 2 weeks for initial NAD+ repletion, followed by monthly maintenance. It is the treatment of choice for patients pursuing proactive ageing interventions, those with chronic fatigue or neurodegenerative concerns, and individuals seeking cognitive enhancement.