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NIPT — TRISOMY Test (Non-Invasive Prenatal Testing)

Type

Blood Testing

Biomarkers

5

Duration

30 min

Sample

Blood (venous draw)

What's included

3 deliverables in this treatment

  • Venous blood draw at G-CENTRUM Olomouc
  • SPADIA laboratory NGS analysis for selected chromosomal conditions
  • Results report and consultation with G-CENTRUM perinatologist

Non-invasive prenatal testing (NIPT) at G-CENTRUM Olomouc analyses cell-free fetal DNA circulating in the mother's blood to screen for chromosomal conditions with 99% accuracy — far exceeding the 85–90% detection rate of standard combined screening. The clinic uses the TRISOMY test platform via SPADIA laboratory. A single blood draw from week 11 of pregnancy is all that is required; results are returned without any risk to the fetus (unlike amniocentesis or CVS). Four tiers of the test are available depending on how many conditions need to be screened.

About this treatment

Non-invasive prenatal testing (NIPT) analyses fragments of cell-free fetal DNA (cffDNA) that circulate in the maternal bloodstream from as early as 7–10 weeks of gestation. From approximately week 11, the fetal fraction is high enough for reliable analysis. G-CENTRUM Olomouc offers NIPT via the TRISOMY test platform run by SPADIA laboratory — a well-established Czech prenatal diagnostic laboratory.

The test requires a single venous blood draw at the clinic. The sample is sent to SPADIA for next-generation sequencing (NGS) analysis, which counts chromosomal fragments and identifies over- or under-representation indicating aneuploidy. Results are reported with >99% sensitivity and specificity for Trisomy 21 (Down syndrome), Trisomy 18 (Edwards syndrome), and Trisomy 13 (Patau syndrome) — the three most common chromosomal conditions detectable in the…

Four test levels are available:

Good to know

Detection accuracy
>99% for Trisomy 21, 18, 13
Available from
Week 11 of gestation
Sample
Single maternal blood draw — no fetal risk
Lab partner
SPADIA laboratory (Czech Republic)
Tiers available
Basic / XY / Plus / Complete

Who is this for?

Pregnant women from 11 weeks who want high-accuracy chromosomal screening without the miscarriage risk of invasive testing, particularly those with screen-positive combined screening results or advanced maternal age

Preparation required

A referral from a gynecologist is required. No fasting needed. The blood draw takes 10–15 minutes. Results are typically returned within 7–10 working days.

Panel categories

Infectious Disease Panel Pregnancy Health Panel

Biomarkers tested

5
HBsAg
Hepatitis B Surface Antibody IU/mL

Indicates immunity against HBV due to vaccination or previous infection.

Hepatitis C (anti-HCV) reactive/non-reactive

Detects antibodies to hepatitis C virus, indicating current or past infection. A positive result requires confirmatory RNA testing. Hepatitis C is now curable with direct-acting antiviral medications in most patients.

HIV 1/2
pH pH units

Imbalances in gut pH influence short-chain fatty acid production and their effects.

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

Clinical team

G-CENTRUM Olomouc is led by founder MUDr. Aleš Skřivánek, Ph.D., a gynecologist with over 35 years of clinical experience practicing since 1989. The team includes MUDr. Iveta Humlová, MUDr. Eva Hajkrová, MUDr. Jana Jelínková, and MUDr. Tomáš Kilián for outpatient gynecology and prenatal care. Urogynecology is covered by MUDr. Radovan Vrtal, Ph.D. and MUDr. Lukáš Kučera. Infertility diagnosis is managed by MUDr. Jan…

Languages: cs, en

What clients say

"{"author":"Andrea Musálková","text":"Pan doktor je velmi profesionální, vše dokáže dokonale vysvětlit i poradit. Má super lidský přístup.","platform":"ZnámýLékař.cz","translated":"The doctor is very professional, can explain everything perfectly and give advice. He has a great human approach."}"

"{"author":"NŠ","text":"Nejlepší gynekolog široko daleko. Pan doktor opravdu ví, co dělá.","platform":"ZnámýLékař.cz","translated":"The best gynecologist far and wide. The doctor really knows what he is doing."}"

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