Calcium Hydroxyapatite Biostimulator (Radiesse / HArmonyCA)

Esthea Medical offers calcium hydroxyapatite (CaHA) biostimulator injections using Radiesse and HArmonyCA — collagen-stimulating injectables that firm and tighten the skin of the face, neck, décolletage and hands. Unlike standard hyaluronic acid fillers, which primarily add volume, CaHA microspheres act as a scaffold that stimulates the skin's own fibroblasts to produce new collagen over the following months, producing a progressive lifting and firming effect with natural-looking results. The treatment is well suited to skin laxity, loss of facial contour definition, and crepey skin on the neck and hands.

Calcium hydroxyapatite is a biostimulatory injectable: microscopic CaHA spheres — chemically identical to the mineral component of bone and fully biocompatible — are suspended in a gel carrier and injected into the deep dermis. The gel provides an immediate, modest volumising effect; over the following 2–6 months, the microspheres stimulate fibroblasts to lay down new type I collagen and elastin around them, progressively improving skin firmness, thickness and contour. The spheres are then gradually metabolised, leaving the newly built collagen behind. **Products used at Esthea Medical:** - *Radiesse (Merz)* — the original and most studied CaHA product, used for firming skin of the face, neck, décolletage and hands and for restoring contour definition (often diluted/hyperdiluted for pure biostimulation across larger areas). - *HArmonyCA (Allergan)* — a hybrid injectable combining CaHA microspheres with cross-linked hyaluronic acid in one syringe, giving an immediate HA lift plus the longer-term collagen-stimulating effect. Both options are priced at 12,000 Kč per treatment. **What it treats:** Skin laxity and loss of firmness in the cheeks and lower face, blurring of the jawline, crepey skin on the neck and décolletage, and volume loss with prominent tendons and veins on the backs of the hands. It is frequently chosen by patients in their 40s–60s who want firmer, better-supported skin without an overfilled look. **The procedure:** After consultation, the physician injects the product with a fine needle or cannula; treatment takes 30–45 minutes. Mild swelling, redness or bruising may occur for a few days. Results develop progressively: an immediate subtle improvement followed by gradually increasing firmness over 2–6 months as collagen builds. Effects typically last 12–18 months, and a series of 1–3 sessions may be recommended depending on skin condition. **Safety:** CaHA has a long clinical record, is fully biodegradable, and is administered here by an aesthetic dermatology physician at a registered healthcare facility. It is not used during pregnancy or breastfeeding or in areas with active skin infection.