Polylactic Acid (PLLA) Collagen Biostimulation — Lenisma / Juvelook

Polylactic acid (PLLA) biostimulation at Estetika by Medfima uses two premium products — Lenisma for facial treatment and Juvelook for the delicate eye area — to trigger the skin's own collagen production over a sustained period. Unlike immediate-acting fillers, PLLA works progressively: microparticles injected under local anaesthesia stimulate fibroblasts directly, producing new collagen that persists long after the PLLA itself has fully biodegraded. The result is a natural, gradual lift and skin thickening that peaks at 2–3 months and can last up to 2 years. Ideal for clients over 35 with initial skin laxity who want subtle, long-lasting improvement without repeated maintenance.

Polylactic acid (PLLA) represents the third generation of injectable biostimulators, and Estetika by Medfima has incorporated it into their treatment menu through two specialist products: Lenisma for broad facial application and Juvelook, a newer-generation PLLA specifically developed for the thin, sensitive periorbital skin that cannot safely receive many traditional fillers or biostimulators. PLLA works through a foreign-body-response mechanism that is both predictable and clinically desirable. Once injected, the microparticles are encapsulated by the body's fibroblasts, which then proliferate and deposit type I and type III collagen fibres around the particles. As the PLLA is gradually biodegraded over 6–8 weeks, it is replaced by this newly synthesised collagen — meaning the structural improvement is entirely the client's own tissue, not a foreign substance. This is why the results of a complete PLLA series can last up to 2 years, far longer than any HA filler. At Estetika by Medfima, the treatment begins with a consultation to identify target areas — most commonly the cheeks, temples, jawline, neck, and décolletage for Lenisma, and the crow's feet and upper eyelid region for Juvelook — and to determine the number of sessions required. Local anaesthesia or topical numbing cream is applied before injection, producing only a mild pressure sensation during the procedure. Sessions are spaced 4–6 weeks apart, allowing time for collagen deposition between treatments. Because PLLA results are gradual and cumulative, they look entirely natural — no sudden volume or the 'done' appearance sometimes associated with conventional fillers. Clients typically notice progressive skin thickening, improved firmness, and a gentle lift emerging over weeks. The full effect is visible at 2–3 months after the final session in the series. Annual top-up treatments are not always required; many clients return only at the 18–24 month mark. PLLA biostimulation is suitable for active, image-conscious individuals from their mid-30s onward who are beginning to notice skin laxity, particularly in the mid-face and around the eyes. It is also effective for body areas including above the knees, inner arms, and the gluteal region where skin thinning creates crepiness. The Juvelook periorbital protocol specifically addresses an area that is frequently undertreated because of its technical difficulty — the thinness of the skin and the proximity of the eye require a physician with both aesthetic knowledge and precise injection technique, which the Medfima team provides. Contraindications are similar to other injectables: pregnancy and breastfeeding, active inflammation at the target site, and autoimmune conditions. Post-procedure, mild swelling at injection sites settles within 2–3 days. Avoid sun exposure and saunas for one week. Occasional small lumps at injection sites can occur if recommended massage protocol is not followed — the physician provides specific massage instructions for the PLLA area during the post-procedure briefing.