


Type
Fat Dissolving
Duration
1 hour
What's included
4 deliverables in this treatment
- Assessment of fat deposit characteristics and suitability for lipolysis by MUDr. Handlová
- Phosphatidylcholine + L-carnitine + anaesthetic lipolytic solution injection at 10–13 mm depth
- Post-injection cooling and immediate care for the inflammatory response
- Aftercare guidance for the 1-week swelling and bruising period
Injectable fat reduction targeting localised subcutaneous deposits using a phosphatidylcholine-based lipolytic solution combined with L-carnitine, a local anaesthetic and homeopathic compounds. The solution is injected at 10–13 mm depth into the subcutaneous fat layer, where phosphatidylcholine disrupts the fat cell membrane, releasing the fat for elimination by the body's lymphatic and metabolic clearance. At Estetické centrum Praha MUDr. Renata Handlová uses this technique for double chin, abdomen, flanks and other localised deposits that resist diet and exercise.
About this treatment
Injection lipolysis uses the membrane-disrupting properties of phosphatidylcholine (PPC) — a phospholipid naturally present in cell membranes and bile — to selectively destroy adipocytes (fat cells) in the subcutaneous layer when injected in therapeutic concentration. PPC at the doses used for lipolysis emulsifies the fat cell membrane, causing the adipocyte to lyse and release its triglyceride content. The freed fatty acids are then processed by…
At Estetické centrum Praha MUDr. Renata Handlová prepares a lipolytic cocktail containing phosphatidylcholine combined with L-carnitine (which facilitates fatty acid transport into mitochondria for beta-oxidation, enhancing elimination), a local anaesthetic to improve comfort during and after injection, and homeopathic supporting compounds. The solution is injected at 10–13 mm depth — reaching the subcutaneous fat layer — at multiple points across the…
The inflammatory response following injection lipolysis is pronounced and predictable: the area becomes swollen, warm, tender and may show bruising within hours of treatment, peaking over the first two to three days and substantially resolving within one week. This inflammatory phase is integral to the clearance mechanism — macrophages migrate to the treated area specifically to process the lysed fat cells. Patients should plan for one week of social…
Good to know
- Active agents
- Phosphatidylcholine + L-carnitine + local anaesthetic
- Injection depth
- 10–13 mm (subcutaneous fat layer)
- Downtime
- Swelling + bruising up to 1 week
- Result permanence
- Long-lasting — destroyed fat cells do not regenerate
Who is this for?
Adults with localised subcutaneous fat deposits (double chin, abdomen, flanks, inner thighs) that persist despite diet and exercise, who prefer a non-surgical injectable approach
Preparation required
Avoid aspirin, ibuprofen, warfarin and alcohol for 48 hours before treatment. Plan for 1 week of social downtime due to swelling and bruising. Inform the doctor of any soy or egg allergy and of all current medications.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
70 clinic reviews
From independent platforms
Clinical team
Estetické centrum Praha is founded and solely operated by MUDr. Renata Handlová. She graduated from the Faculty of General Medicine, Charles University Prague in 1986. Until 1994 she worked at the I. Eye Clinic of the General Teaching Hospital (Prague 2), followed by a period as an ophthalmologist at Královské Vinohrady Teaching Hospital. Since 1998 she has practised aesthetic dermatology as a supplementary…
Languages: Czech
What clients say
"Excellent doctor, extremely precise and knowledgeable. I have been coming for botulotoxin for years and the results are always natural. — Google review"
"Professional approach, clean clinic, very satisfied with the results of my filler treatment. The doctor explains everything thoroughly. — Google review"
Treatment highlights
- Assessment of fat deposit characteristics and suitability for lipolysis by MUDr. Handlová
- Phosphatidylcholine + L-carnitine + anaesthetic lipolytic solution injection at 10–13 mm depth
+2 more items in What's included
From 4,000 Kč per 1 ml of lipolytic solution. Volume required depends on the size of the treatment area — typically 10–13 ml per session for a localised deposit. Multiple sessions may be needed. Bruising and swelling for up to 1 week after each session should be planned for. Call +420 775 077 055.
